6-Hydroxychlorzoxazone
6-Hydroxychlorzoxazone (CAS: 1750-45-4) is a chemical compound with the molecular formula C7H4ClNO3 and a molecular weight of 185.56 g/mol. It serves as a key metabolite of chlorzoxazone, primarily generated by CYP2E1 and CYP1A2 enzymes. Available in a white to pink appearance with an assay of ≥98%, this compound is valuable for research in drug metabolism and xenobiotic studies within cell biology and neuroscience.
- IUPAC
- 5-Chloro-6-hydroxy-2(3H)-benzoxazolone,5-Chloro-6-hydroxybenzoxazone
- Synonyms
- 5-Chloro-6-hydroxy-2(3H)-benzoxazolone5-Chloro-6-hydroxybenzoxazone
Drug Metabolism Studies
Investigate the metabolic pathways of chlorzoxazone, particularly its biotransformation mediated by cytochrome P450 enzymes like CYP2E1 and CYP1A2. Useful for understanding drug clearance and pharmacokinetics.
Enzyme Activity Research
Employ as a standard or substrate in assays to study the activity and inhibition profiles of specific drug-metabolizing enzymes. Aids in evaluating potential drug-drug interactions.
Xenobiotic Metabolism Research
Utilise in studies focusing on how the body processes foreign compounds (xenobiotics), providing insights into detoxification mechanisms and potential toxicity.
Cellular Signaling Research
Explore its role or influence within cellular signaling pathways, particularly in contexts related to neuroscience and cell biology research.
| Molecular weight | 185.56 |
|---|---|
| Empirical formula | C7H4ClNO3 |
| Assay | ≥98% (HPLC) |
| Colour | white to pink |
| Solubility | methanol: soluble |
| Storage temperature | 2-8°C |
| Application | CYP2E1 & 1A2 metabolite of chlorzoxazone. |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6-Hydroxychlorzoxazone used for?
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6-Hydroxychlorzoxazone is primarily used in research to study the metabolism of chlorzoxazone by enzymes such as CYP2E1 and CYP1A2. It is valuable for investigating drug and xenobiotic metabolism, as well as cellular signaling pathways.
What is the CAS number and formula for 6-Hydroxychlorzoxazone?
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The CAS number for 6-Hydroxychlorzoxazone is 1750-45-4, and its empirical formula is C7H4ClNO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 6-Hydroxychlorzoxazone with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade.
How should 6-Hydroxychlorzoxazone be handled and stored?
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Handle 6-Hydroxychlorzoxazone with appropriate personal protective equipment, including a dust mask (N95 recommended), eyeshields, and gloves. Store at 2-8°C. It may cause skin irritation (H315), eye irritation (H319), and respiratory irritation (H335).
Is 6-Hydroxychlorzoxazone a controlled substance?
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The provided data does not indicate that 6-Hydroxychlorzoxazone is a controlled substance.
How is 6-Hydroxychlorzoxazone shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, capable of shipping and exporting 6-Hydroxychlorzoxazone worldwide according to relevant regulations.
How can I request a sample or quote for 6-Hydroxychlorzoxazone?
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To request a sample or a quote for 6-Hydroxychlorzoxazone, please contact our sales department through the TSS website or via the provided contact information.
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