6-Hydroxydopamine hydrochloride
6-Hydroxydopamine hydrochloride (CAS 28094-15-7), with the linear formula (HO)3C6H2CH2CH2NH2·HCl and a molecular weight of 205.64, is a fine chemical supplied by Tech Serve Solutions. This off-white to brown powder is primarily utilised in neuroscience research for its ability to selectively destroy dopaminergic and noradrenergic neurons. Its applications are centred on experimental models of Parkinson's disease and other neurodegenerative conditions, aiding in the study of neurotransmitter systems.
- IUPAC
- 2,4,5-Trihydroxyphenethylamine hydrochloride,2,5-Dihydroxytyramine hydrochloride,2-(2,4,5-Trihydroxyphenyl)ethylamine hydrochloride,6-OHDA
- Synonyms
- 2,4,5-Trihydroxyphenethylamine hydrochloride2,5-Dihydroxytyramine hydrochloride2-(2,4,5-Trihydroxyphenyl)ethylamine hydrochloride6-OHDA
Neuroscience Research
6-Hydroxydopamine hydrochloride is a crucial tool in neuroscience for creating animal models of neurodegenerative diseases. It is used to induce selective lesions in dopaminergic pathways, mimicking aspects of Parkinson's disease for research purposes.
Cell Biology Studies
This compound serves as a biochemical probe in cell biology, particularly in studies involving catecholamine systems. Researchers use it to investigate cellular responses and signalling pathways affected by dopamine and norepinephrine depletion.
Neurotransmitter System Investigation
It aids in the study of neurotransmission by selectively damaging neurons that utilise dopamine and noradrenaline. This allows for a better understanding of the roles these neurotransmitters play in various physiological and pathological processes.
| Molecular weight | 205.64 |
|---|---|
| Linear formula | (HO)3C6H2CH2CH2NH2 · HCl |
| Assay | >97% (titration) |
| Form | powder |
| Colour | off-white to brown |
| Solubility | H2O: >50 mg/mL, clear, yellow to brown |
| Storage temperature | room temp |
| Melting point | 232-233 °C (dec.)(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6-Hydroxydopamine hydrochloride used for?
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6-Hydroxydopamine hydrochloride (CAS 28094-15-7) is primarily used in neuroscience research to create experimental models of neurodegenerative conditions, such as Parkinson's disease, by selectively destroying dopaminergic and noradrenergic neurons. It also serves as a tool in cell biology for studying catecholamine systems and neurotransmission.
What are the CAS number and formula for 6-Hydroxydopamine hydrochloride?
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The CAS number for 6-Hydroxydopamine hydrochloride is 28094-15-7. Its linear formula is (HO)3C6H2CH2CH2NH2·HCl.
What grade and purity does Tech Serve Solutions supply for 6-Hydroxydopamine hydrochloride?
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Tech Serve Solutions supplies 6-Hydroxydopamine hydrochloride with an assay of >97% by titration. This product is intended for research and laboratory use. TSS does not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should 6-Hydroxydopamine hydrochloride be handled safely?
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According to GHS guidelines, 6-Hydroxydopamine hydrochloride is a Warning substance with hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves, should be used. Handle in a well-ventilated area and avoid dust formation.
How is 6-Hydroxydopamine hydrochloride packed, shipped, and exported?
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Tech Serve Solutions professionally packs, ships, and exports 6-Hydroxydopamine hydrochloride according to international regulations for fine chemicals. Specific packaging details are available upon request for your order.
How can I request a sample or quote for 6-Hydroxydopamine hydrochloride?
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To request a sample or a quote for 6-Hydroxydopamine hydrochloride, please contact our sales team through the website or by phone. Provide your contact details and the quantity required.
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