Epoxomicin
Epoxomicin (CAS: 134381-21-8) is a potent and selective proteasome inhibitor. This chemical compound is recognised for its biological activity, acting as a powerful tool in biochemical research. It is primarily utilised to investigate cellular processes, particularly those involving protein degradation pathways regulated by the proteasome. Epoxomicin's specificity makes it valuable for understanding enzyme function and developing targeted therapeutic strategies.
- IUPAC
- N-Acetyl-N-methyl-L-isoleucyl-L-isoleucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyloxiranyl]carbonyl]butyl]-L-threoninamide

Proteasome Inhibition Studies
Epoxomicin is extensively used as a research chemical to inhibit proteasome activity. This allows scientists to study the role of protein degradation in various cellular functions and disease mechanisms.
Biochemical and Cell Signalling Research
As a key biochemical reagent, Epoxomicin aids in exploring cell signalling pathways. Its ability to block proteasome function helps elucidate complex biological processes at the molecular level.
Enzyme Activity Investigation
This compound serves as an inhibitor to investigate the activity and mechanisms of proteasomes and related proteases. Researchers employ Epoxomicin to understand enzyme kinetics and substrate interactions.
| Assay | ≥95% (HPLC) |
|---|---|
| Form | solid |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Epoxomicin used for?
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Epoxomicin is used as a potent and selective proteasome inhibitor in biochemical and cell signalling research. It is employed to study protein degradation pathways and enzyme activity.
What is the CAS number and chemical formula for Epoxomicin?
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The CAS number for Epoxomicin is 134381-21-8. The chemical formula is N-Acetyl-N-methyl-L-isoleucyl-L-isoleucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyloxiranyl]carbonyl]butyl]-L-threoninamide.
What grade and purity does Tech Serve Solutions supply for Epoxomicin?
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Tech Serve Solutions supplies Epoxomicin with a purity of ≥95% (HPLC). This product is intended for research purposes and is not represented as USP, BP, or EP grade.
How should Epoxomicin be handled safely?
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Safe handling of Epoxomicin requires appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. Users should consult the Safety Data Sheet (SDS) for detailed hazard information.
How is Epoxomicin packaged, shipped, and exported by TSS?
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Epoxomicin is typically supplied as a solid and stored at -20°C. Tech Serve Solutions professionally packages, handles, and exports this chemical globally, adhering to all relevant shipping regulations.
How can I request a sample or quote for Epoxomicin?
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To request a sample or a quote for Epoxomicin, please contact the Tech Serve Solutions sales team through our website or by phone. Our team will be happy to assist you.
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