Fmoc-Lys(Tfa)-OH
Nα-Fmoc-Nε-trifluoroacetyl-L-lysine (CAS 76265-69-5) is a protected amino acid derivative with the molecular formula C23H23F3N2O5 and a molecular weight of 464.43 g/mol. This compound is primarily utilised in peptide synthesis, offering a protected form of lysine for incorporation into complex peptide chains. Its trifluoroacetyl group provides robust protection for the epsilon-amino group during solid-phase peptide synthesis and other biochemical research applications.
- IUPAC
- Nα-Fmoc-Nε-trifluoroacetyl-L-lysine
Peptide Synthesis
This Fmoc-protected lysine derivative is a key building block in solid-phase peptide synthesis (SPPS). The Nα-Fmoc group facilitates orthogonal deprotection strategies, while the Nε-trifluoroacetyl group protects the side-chain amine during coupling reactions.
Chemical Biology Research
Used in the construction of modified peptides for biochemical studies, enabling researchers to investigate protein function, drug discovery, and biological pathways through the precise assembly of amino acid sequences.
Organic Synthesis
Serves as a versatile intermediate in complex organic synthesis, particularly where modified amino acid functionalities are required for the creation of novel molecules and materials.
| Molecular weight | 464.43 |
|---|---|
| Empirical formula | C23H23F3N2O5 |
| Assay | ≥96.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Nα-Fmoc-Nε-trifluoroacetyl-L-lysine used for?
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Nα-Fmoc-Nε-trifluoroacetyl-L-lysine is primarily used as a protected amino acid derivative in peptide synthesis and chemical biology research.
What is the CAS number and molecular formula?
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The CAS number is 76265-69-5 and the molecular formula is C23H23F3N2O5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Nα-Fmoc-Nε-trifluoroacetyl-L-lysine with an assay of ≥96.0% (HPLC). We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling requirements?
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When handling this compound, it is essential to use safety measures including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if necessary. This compound has a WGK Germany classification of 3, indicating it is hazardous to water.
How is this product shipped and exported?
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This product is typically stored at 2-8°C. Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals.
How can I request a sample or quote?
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Please contact our sales team directly through our website to request a sample or a quotation for Nα-Fmoc-Nε-trifluoroacetyl-L-lysine.
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