Fmoc-Met-OH
Fmoc-Met-OH (CAS: 71989-28-1), with the molecular formula C20H21NO4S and a molecular weight of 371.45 g/mol, is a key building block in peptide synthesis. This N-protected amino acid derivative is crucial for solid-phase peptide synthesis (SPPS) and solution-phase methodologies. Its application is essential for creating complex peptide chains and modified peptides, contributing significantly to research in chemical biology and drug discovery.
- IUPAC
- Fmoc-L-methionine
Peptide Synthesis
Fmoc-Met-OH is widely employed in solid-phase and solution-phase peptide synthesis. The Fmoc protecting group allows for controlled deprotection and coupling steps, enabling the stepwise assembly of peptide sequences.
Chemical Biology Research
This compound serves as a valuable reagent for researchers in chemical biology, facilitating the synthesis of peptides with specific modifications for studying biological processes and developing novel therapeutics.
Pharmaceutical Intermediate
As a derivative of methionine, Fmoc-Met-OH acts as an intermediate in the synthesis of various pharmaceutical compounds and peptide-based drugs, contributing to advancements in medicinal chemistry.
| Molecular weight | 371.45 |
|---|---|
| Empirical formula | C20H21NO4S |
| Assay | ≥98.0% (HPLC) |
| Optical activity | [α]20/D −30±1°, c = 1% in DMF |
| Storage temperature | 2-8°C |
| Melting point | 121-123 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Met-OH used for?
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Fmoc-Met-OH is primarily used as a protected amino acid in solid-phase and solution-phase peptide synthesis, as well as in chemical biology research and the development of pharmaceutical intermediates.
What are the CAS number and molecular formula for Fmoc-Met-OH?
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The CAS number for Fmoc-Met-OH is 71989-28-1, and its molecular formula is C20H21NO4S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-Met-OH with an assay of ≥98.0% (HPLC). This product is not classified as USP, BP, or EP grade and is intended for research and laboratory use.
How should Fmoc-Met-OH be handled and stored?
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Fmoc-Met-OH should be stored at 2-8°C. When handling, it is essential to use personal protective equipment including eyeshields, gloves, and a type N95 respirator filter.
Is Fmoc-Met-OH a controlled substance?
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Based on the provided data, Fmoc-Met-OH is not indicated as a controlled substance.
How is Fmoc-Met-OH packed, shipped, and exported?
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Fmoc-Met-OH is carefully packed to ensure stability during transport. Tech Serve Solutions, established in 1998, is a specialist global supplier and exporter of fine chemicals, including Fmoc-Met-OH.
How can I request a sample or a quote for Fmoc-Met-OH?
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To request a sample or obtain a quotation for Fmoc-Met-OH, please contact our sales team through the website or by phone.
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