4-Nitrophenyl formate
4-Nitrophenyl formate (CAS: 1865-01-6, C7H5NO4) is a chemical compound with a molecular weight of 167.12 g/mol. It serves as a valuable reagent in organic synthesis, particularly for amine protection and derivatization in peptide chemistry. This compound is essential in research and development settings for the construction of complex molecules and is supplied by Tech Serve Solutions with a purity of ≥97.0% (HPLC).
- IUPAC
- Formic acid 4-nitrophenyl ester
- Synonyms
- Formic acid 4-nitrophenyl ester
Amine Protection Reagent
4-Nitrophenyl formate is employed as a protecting group reagent for amines in organic synthesis. Its controlled reactivity allows for selective protection of amine functionalities during multi-step synthetic pathways.
Peptide Synthesis
In peptide chemistry, this compound can be utilised for derivatization or modification of amino acid residues. This aids in the synthesis of peptides with specific structural or functional properties.
Chemical Biology Research
It finds application in chemical biology for the synthesis of labelled molecules or probes. Its incorporation into biochemical systems can aid in studying biological processes.
Synthetic Reagent
As a general synthetic reagent, 4-Nitrophenyl formate facilitates various esterification and acylation reactions. It is a useful building block in the development of novel chemical entities.
| Molecular weight | 167.12 |
|---|---|
| Empirical formula | C7H5NO4 |
| Assay | ≥97.0% (HPLC) |
| Storage temperature | −20°C |
| Melting point | 71-74 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Nitrophenyl formate used for?
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4-Nitrophenyl formate is primarily used as a reagent for amine protection and derivatization in organic synthesis, particularly in peptide chemistry and chemical biology research.
What is the CAS number and chemical formula for 4-Nitrophenyl formate?
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The CAS number is 1865-01-6, and the chemical formula is C7H5NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Nitrophenyl formate with an assay of ≥97.0% (HPLC). This is a research-grade chemical and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should 4-Nitrophenyl formate be handled safely?
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Handle 4-Nitrophenyl formate with appropriate personal protective equipment, including eyeshields and gloves. Use a type N95 (US) or type P1 (EN143) respirator filter for respiratory protection. It is classified as WGK 3 in Germany, indicating a high hazard level.
How is 4-Nitrophenyl formate shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, ensuring compliant packaging and documentation for international shipments.
How can I request a sample or quote for 4-Nitrophenyl formate?
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To request a sample or obtain a quote, please contact the Tech Serve Solutions sales team through our website or by phone, referencing the product name and CAS number (1865-01-6).
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