Fmoc-N-Me-Glu(OtBu)-OH
Fmoc-N-Me-Glu(OtBu)-OH (CAS: 200616-40-6), a derivative of N-methyl glutamic acid with the empirical formula C25H29NO6 and molecular weight 439.50, is a key building block in peptide chemistry. This Fmoc-protected unnatural amino acid derivative offers enhanced biological stability in peptides compared to standard amino acids, making it valuable for research in chemical biology and synthesis.
- IUPAC
- N-Methyl glutamic acid
Peptide Synthesis
Utilised as an Fmoc-protected unnatural amino acid building block in solid-phase and solution-phase peptide synthesis. Its incorporation can enhance peptide stability and alter conformational properties.
Chemical Biology Research
Serves as a tool for constructing peptides with modified properties for investigating biological pathways and protein function. The N-methyl group contributes to increased resistance to enzymatic degradation.
Drug Discovery and Development
A valuable reagent in the synthesis of peptidomimetics and modified peptides aimed at developing novel therapeutic agents with improved pharmacokinetic profiles.
| Molecular weight | 439.50 |
|---|---|
| Empirical formula | C25H29NO6 |
| Assay | 97% |
| Storage temperature | 2-8°C |
| Application | Fmoc-protected N-methyl amino acid. N-methyl amino acids have shown enhanced biological stability in peptides compared to standard amino acids. |
| Melting point | 116-119 °C |
Hazard statements
- H410Very toxic to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
- P501Dispose of contents and container per local regulations
| Transport (UN / ADR) | UN 3077 9 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | N |
| Risk statements (R) | 50/53 |
| Safety statements (S) | 60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-N-Me-Glu(OtBu)-OH used for?
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Fmoc-N-Me-Glu(OtBu)-OH is used in peptide synthesis and chemical biology research as an Fmoc-protected N-methyl amino acid derivative. It offers enhanced biological stability in peptides compared to standard amino acids.
What are the CAS number and formula for Fmoc-N-Me-Glu(OtBu)-OH?
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The CAS number is 200616-40-6 and the empirical formula is C25H29NO6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-N-Me-Glu(OtBu)-OH with an assay of 97%. We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.
What are the safety and handling considerations for Fmoc-N-Me-Glu(OtBu)-OH?
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Fmoc-N-Me-Glu(OtBu)-OH is classified under GHS09 with the signal word Warning. It carries hazard statement H410 (Very toxic to aquatic life with long lasting effects). Handle with appropriate personal protective equipment and avoid release to the environment (P273-P501).
How is Fmoc-N-Me-Glu(OtBu)-OH packed, shipped, and exported?
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Fmoc-N-Me-Glu(OtBu)-OH is stored at 2-8°C. It is shipped as UN 3077, Class 9, Packing Group III, environmentally hazardous substance.
How can I request a sample or quote for Fmoc-N-Me-Glu(OtBu)-OH?
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Please contact the Tech Serve Solutions sales team via our website or direct contact details to request a sample or obtain a quotation for Fmoc-N-Me-Glu(OtBu)-OH.
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