Fmoc-N-Me-Nle-OH
Fmoc-N-Me-Nle-OH (CAS: 112883-42-8), with the molecular formula C22H25NO4 and a molecular weight of 367.44 g/mol, is a specialised N-methyl amino acid derivative. It is a key building block utilised in peptide chemistry and synthesis. This compound facilitates the incorporation of unnatural amino acid analogues into peptide chains, offering unique structural and functional properties. Its primary applications are found within chemical biology and advanced chemical synthesis research.
- IUPAC
- Fmoc-N-methyl-L-norleucine
Peptide Synthesis
Fmoc-N-Me-Nle-OH serves as a valuable N-methylated amino acid building block in solid-phase and solution-phase peptide synthesis. It enables the creation of modified peptides with altered conformational stability and biological activity.
Chemical Biology Research
This compound is employed in chemical biology to synthesise peptides or peptidomimetics incorporating unnatural amino acids. These modified molecules can be used to probe biological pathways or develop novel therapeutic agents.
Drug Discovery and Development
As an unnatural amino acid derivative, Fmoc-N-Me-Nle-OH contributes to the development of novel peptide-based drugs. Its incorporation can enhance metabolic stability and receptor binding affinity of therapeutic peptides.
Organic Synthesis
Beyond peptide chemistry, this molecule finds utility in general organic synthesis where N-methylated amino acid structures are required for constructing complex organic molecules.
| Molecular weight | 367.44 |
|---|---|
| Empirical formula | C22H25NO4 |
| Assay | ≥96.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-N-Me-Nle-OH primarily used for?
+
Fmoc-N-Me-Nle-OH is primarily used as a building block in peptide synthesis and chemical biology research, particularly for incorporating N-methylated and unnatural amino acid residues into peptide chains.
What are the CAS number and formula for Fmoc-N-Me-Nle-OH?
+
The CAS number for Fmoc-N-Me-Nle-OH is 112883-42-8, and its molecular formula is C22H25NO4.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Fmoc-N-Me-Nle-OH with an assay of ≥96.0% (HPLC). This product is intended for research and laboratory use and is not represented as USP, BP, or EP grade.
What are the safety and handling recommendations for Fmoc-N-Me-Nle-OH?
+
Handling Fmoc-N-Me-Nle-OH requires appropriate personal protective equipment, including eyeshields and gloves. In environments with potential for aerosol exposure, use of a type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound is classified with WGK Germany of 3, indicating a high hazard to water.
How is Fmoc-N-Me-Nle-OH stored and shipped?
+
Fmoc-N-Me-Nle-OH should be stored at temperatures between 2-8°C. Tech Serve Solutions exports this chemical globally, adhering to all relevant shipping and handling regulations.
How can I request a sample or quote for Fmoc-N-Me-Nle-OH?
+
To request a sample or a quotation for Fmoc-N-Me-Nle-OH, please contact our sales team through the provided channels on the Tech Serve Solutions website.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis