Fmoc-N-Me-Thr(tBu)-OH
Fmoc-N-Me-Thr(tBu)-OH (CAS: 117106-20-4, C24H29NO5) is a protected N-methylated amino acid derivative. It features a tert-butyl protecting group on the threonine side chain and an Fmoc protecting group on the amine. This compound is crucial for the synthesis of modified peptides, particularly those incorporating N-methylated amino acids or requiring specific side-chain protection. Its structure facilitates controlled incorporation into peptide chains during solid-phase synthesis.
- IUPAC
- Fmoc-N-methyl-O-tert-butyl-L-threonine
- Synonyms
- Fmoc-N-methyl-O-tert-butyl-L-threonine
Peptide Synthesis
Utilised as a building block in solid-phase peptide synthesis (SPPS) for creating peptides with N-methylated residues. The tert-butyl group offers side-chain protection during synthesis.
Chemical Biology
Serves as a reagent in the development of novel biomolecules and peptidomimetics. Its unique structure aids in studying peptide-protein interactions or developing peptide-based therapeutics.
Organic Synthesis
Employed in complex organic synthesis where a protected N-methylated threonine derivative is required. Enables regioselective derivatisation and coupling reactions.
Unnatural Amino Acid Derivatives
Incorporated into research for creating unnatural amino acids with specific side-chain modifications. Aids in probing or engineering protein function.
| Molecular weight | 411.49 |
|---|---|
| Empirical formula | C24H29NO5 |
| Assay | 97% |
| Optical activity | [α]22/D +16.0°, c = 0.5% in methanol |
| Storage temperature | 2-8°C |
| Melting point | 220-225 °C |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-N-Me-Thr(tBu)-OH used for?
+
Fmoc-N-Me-Thr(tBu)-OH is primarily used as a protected building block in peptide synthesis, especially for incorporating N-methylated and side-chain protected threonine residues into peptide sequences. It is also valuable in chemical biology and general organic synthesis.
What is the CAS number and chemical formula for Fmoc-N-Me-Thr(tBu)-OH?
+
The CAS number is 117106-20-4, and the empirical formula is C24H29NO5.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Fmoc-N-Me-Thr(tBu)-OH with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Fmoc-N-Me-Thr(tBu)-OH be handled and stored?
+
Fmoc-N-Me-Thr(tBu)-OH requires storage at 2-8°C. Handle with appropriate personal protective equipment, as it may cause skin and eye irritation. Refer to the Safety Data Sheet for detailed handling instructions.
Is Fmoc-N-Me-Thr(tBu)-OH a scheduled or controlled substance?
+
The provided data does not indicate that Fmoc-N-Me-Thr(tBu)-OH is a scheduled or controlled substance.
How can I request a sample or quote for Fmoc-N-Me-Thr(tBu)-OH?
+
To request a sample or a quote, please contact our sales team through the website or provide your details via the 'Enquire Now' button on the product page.
How is this chemical exported?
+
Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. This product can be exported internationally, adhering to all relevant shipping regulations.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis