Fmoc-N-Me-Val-OH
Fmoc-N-Me-Val-OH (CAS: 84000-11-3) is a chiral N-methyl amino acid derivative with the molecular formula C21H23NO4 and a molecular weight of 353.41 g/mol. This compound is primarily utilised in peptide chemistry and synthesis, particularly for incorporating N-methylated amino acids into peptide chains. It serves as a valuable building block in chemical biology and unnatural amino acid research, offering modified peptide properties.
- IUPAC
- Fmoc-N-methyl-L-valine
Peptide Synthesis
Fmoc-N-Me-Val-OH is employed in solid-phase and solution-phase peptide synthesis. Its N-methyl group can influence peptide conformation and stability, making it useful for developing peptides with specific structural characteristics.
Chemical Biology
This compound serves as a tool in chemical biology for creating peptides with altered biological activities or improved pharmacokinetic properties. It enables the study of structure-activity relationships in modified peptide systems.
Unnatural Amino Acid Derivatives
As an unnatural amino acid derivative, Fmoc-N-Me-Val-OH is valuable for expanding the repertoire of amino acids available for protein and peptide engineering. Its incorporation can lead to novel biomaterials or therapeutic peptides.
Research and Development
It is utilized in academic and industrial research settings for exploring novel chemical entities and advancing synthetic methodologies in organic chemistry and medicinal chemistry.
| Molecular weight | 353.41 |
|---|---|
| Empirical formula | C21H23NO4 |
| Assay | ≥98.0% (sum of enantiomers, HPLC) |
| Optical activity | [α]20/D −68.0±3°, c = 1% in DMF |
| Storage temperature | 2-8°C |
| Melting point | 187-190 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-N-Me-Val-OH used for?
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Fmoc-N-Me-Val-OH is primarily used as a building block in peptide synthesis, chemical biology research, and for the creation of unnatural amino acid derivatives. It helps in modifying peptide structure and properties.
What are the CAS number and molecular formula for Fmoc-N-Me-Val-OH?
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The CAS number for Fmoc-N-Me-Val-OH is 84000-11-3, and its molecular formula is C21H23NO4.
What grade and purity does Tech Serve Solutions supply for Fmoc-N-Me-Val-OH?
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Tech Serve Solutions supplies Fmoc-N-Me-Val-OH with an assay of ≥98.0% (sum of enantiomers, HPLC). This product is supplied for research and development purposes and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should Fmoc-N-Me-Val-OH be handled safely?
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When handling Fmoc-N-Me-Val-OH, it is essential to use personal protective equipment including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. Appropriate ventilation is also recommended.
How is Fmoc-N-Me-Val-OH packed, shipped, and exported by TSS?
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Fmoc-N-Me-Val-OH is carefully packed and exported by Tech Serve Solutions adhering to international shipping regulations for chemicals. Specific packaging details are available upon request.
How can I request a sample or quote for Fmoc-N-Me-Val-OH?
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To request a sample or quote for Fmoc-N-Me-Val-OH, please contact the Tech Serve Solutions sales team via the website or by telephone. Please specify the quantity required and your delivery location.
Does Fmoc-N-Me-Val-OH (CAS 84000-11-3) have specific storage requirements?
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Yes, Fmoc-N-Me-Val-OH should be stored at a temperature of 2-8°C to maintain its stability and quality.
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