Fmoc-Pen(Trt)-OH
Fmoc-Pen(Trt)-OH (CAS: 201531-88-6; Formula: C39H35NO4S; MW: 613.76) is a protected amino acid derivative crucial in peptide synthesis. It features Fmoc protection for the amine group and a trityl (Trt) protecting group on the sulfur atom of penicillamine. This structure allows for controlled peptide chain elongation in solid-phase and solution-phase synthesis, particularly useful for incorporating unnatural amino acid residues and in chemical biology applications.
- IUPAC
- Fmoc-β,β-dimethyl-Cys(Trt)-OH,Fmoc-S-trityl-L-penicillamine
- Synonyms
- Fmoc-S-trityl-L-penicillamineFmoc-β,β-dimethyl-Cys(Trt)-OH
Peptide Synthesis
Serves as a building block in solid-phase peptide synthesis (SPPS) and solution-phase methods. The Fmoc group enables base-labile deprotection, facilitating sequential amino acid coupling.
Chemical Biology
Utilised in the creation of modified peptides for probing biological pathways and developing novel therapeutics. Its unique structure allows for specific functionalisation.
Unnatural Amino Acid Incorporation
Facilitates the incorporation of penicillamine-derived, unnatural amino acids into peptide sequences, expanding the chemical diversity of peptides for research.
Drug Discovery and Development
A key intermediate in the synthesis of peptidomimetics and peptide-based drug candidates, contributing to the development of new pharmaceutical agents.
| Molecular weight | 613.76 |
|---|---|
| Empirical formula | C39H35NO4S |
| Assay | ≥95.5% (HPLC)96% |
| Optical activity | [α]/D +33±2°, c = 1 in methanol |
| Storage temperature | 2-8°C |
Hazard statements
- H413May cause long-lasting harmful effects to aquatic life
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Pen(Trt)-OH used for?
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Fmoc-Pen(Trt)-OH is primarily used as a protected amino acid building block in peptide synthesis, particularly for incorporating unnatural amino acid residues and in chemical biology research.
What is the CAS number and molecular formula for Fmoc-Pen(Trt)-OH?
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The CAS number for Fmoc-Pen(Trt)-OH is 201531-88-6, and its molecular formula is C39H35NO4S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-Pen(Trt)-OH with an assay of ≥95.5% (HPLC) or 96%. TSS does not represent this product as USP, BP, or EP grade.
How should Fmoc-Pen(Trt)-OH be handled and stored?
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Handle with appropriate personal protective equipment including eyeshields and gloves. A respirator filter (type N95 or P1) is recommended. Store at 2-8°C. Dispose of waste according to regulations, considering its H413 hazard statement.
Is Fmoc-Pen(Trt)-OH a controlled substance?
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The provided data does not indicate that Fmoc-Pen(Trt)-OH is a controlled substance.
How is Fmoc-Pen(Trt)-OH packed and shipped?
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Fmoc-Pen(Trt)-OH is carefully packed for stability and safe transport. TSS is experienced in exporting chemicals globally. Please contact us for specific packaging and shipping inquiries.
How can I request a quote or sample for Fmoc-Pen(Trt)-OH?
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To request a quote or sample of Fmoc-Pen(Trt)-OH, please use the contact form on our website or email our sales department directly. Specify the quantity required.
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