Fmoc-Phe(2-CN)-OH

CAS 401933-16-2C25H20N2O4Chemical Synthesis

Fmoc-Phe(2-CN)-OH (CAS: 401933-16-2) is a specialised unnatural amino acid derivative with the molecular formula C25H20N2O4 and a molecular weight of 412.44 g/mol. This compound is primarily utilised in chemical synthesis, particularly within peptide chemistry and chemical biology research. It serves as a building block for creating peptides containing modified amino acid residues, enabling the exploration of novel biochemical pathways and therapeutic targets.

IUPAC: Fmoc-2-cyano-L-phenylalanine

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Fmoc-Phe(2-CN)-OH (C25H20N2O4) — chemical structure, CAS 401933-16-2; Chemistry, fine chemical supplied by Tech Serve Solutions

Chemical BiologyChemical SynthesisPeptide ChemistryPhenylalanine Derivatives

01 /Applications

Peptide Synthesis

Serves as a key building block in solid-phase or solution-phase peptide synthesis for incorporating unnatural amino acid residues.

Chemical Biology Research

Facilitates the study of protein structure-function relationships and the development of peptide-based probes or inhibitors.

Medicinal Chemistry

Utilised in the design and synthesis of novel peptidomimetics and drug candidates with enhanced stability or altered biological activity.

Organic Synthesis

Acts as a valuable reagent in complex organic synthesis for constructing molecules with specific chiral centres and functionalities.

02 /Properties

Molecular weight	412.44
Empirical formula	C25H20N2O4
Assay	≥98.0% (HPLC)
Storage temperature	2-8°C

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P305IF IN EYES

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	36/37/38
Safety statements (S)	36/37/39

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

401933-16-2

MDL number

MFCD01863771

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Fmoc-Phe(2-CN)-OH used for?

Fmoc-Phe(2-CN)-OH is primarily used as a building block in peptide synthesis, chemical biology research, medicinal chemistry, and organic synthesis.

What is the CAS number and formula for Fmoc-Phe(2-CN)-OH?

The CAS number is 401933-16-2 and the empirical formula is C25H20N2O4.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Fmoc-Phe(2-CN)-OH with an assay of ≥98.0% (HPLC). We do not represent this product as USP, BP, EP, or any pharmacopoeia grade.

How should Fmoc-Phe(2-CN)-OH be handled safely?

Handle with appropriate personal protective equipment, including eyeshields and gloves. Ensure adequate ventilation or use a suitable respirator filter (type N95 or P1). Avoid breathing dust. May cause skin, eye, and respiratory irritation (H315, H319, H335).

How is Fmoc-Phe(2-CN)-OH typically shipped or exported?

Fmoc-Phe(2-CN)-OH is typically stored at 2-8°C. Shipments are handled by experienced logistics professionals adhering to all necessary regulations for chemical export.