Fmoc-Phe(2-Br)-OH
Fmoc-Phe(2-Br)-OH (CAS: 220497-47-2) is a brominated phenylalanine derivative protected with the Fmoc group. This specialised amino acid analogue serves as a valuable building block in complex organic synthesis and peptide chemistry. Its structure allows for the introduction of a modified phenylalanine residue into peptide chains, facilitating research in chemical biology and drug discovery.
- IUPAC
- Fmoc-2-bromo-L-phenylalanine
Peptide Synthesis
Fmoc-Phe(2-Br)-OH is employed in solid-phase and solution-phase peptide synthesis. It allows for the incorporation of a 2-bromo-L-phenylalanine residue, useful for creating modified peptides with altered biological activities or for subsequent cross-coupling reactions.
Chemical Biology Research
This compound is utilised in chemical biology to construct peptides or peptidomimetics with specific structural or functional modifications. The bromine atom can serve as a handle for further chemical derivatisation or for incorporation into probes.
Organic Synthesis
As a functionalised amino acid, Fmoc-Phe(2-Br)-OH is a versatile intermediate in the synthesis of complex organic molecules. Its unique substitution pattern makes it suitable for advanced synthetic strategies.
| Molecular weight | 466.32 |
|---|---|
| Empirical formula | C24H20BrNO4 |
| Assay | ≥98.0% (HPLC) |
Hazard statements
- H413May cause long-lasting harmful effects to aquatic life
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Phe(2-Br)-OH used for?
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Fmoc-Phe(2-Br)-OH is primarily used as a building block in peptide synthesis and for research in chemical biology and organic synthesis, allowing for the introduction of a modified phenylalanine residue.
What is the CAS number and molecular formula for Fmoc-Phe(2-Br)-OH?
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The CAS number is 220497-47-2 and the empirical formula is C24H20BrNO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-Phe(2-Br)-OH with an assay of ≥98.0% (HPLC). This product is supplied for research and development purposes and is not represented as USP, BP, EP, or other pharmacopoeia grades.
What are the safety and handling considerations for Fmoc-Phe(2-Br)-OH?
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Fmoc-Phe(2-Br)-OH may cause long-lasting harmful effects to aquatic life (H413). Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Store in a well-ventilated place and keep container tightly closed.
How is Fmoc-Phe(2-Br)-OH packed and shipped?
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Fmoc-Phe(2-Br)-OH is carefully packed according to international shipping regulations to ensure product integrity and safety during transit. Tech Serve Solutions is a global supplier and exporter.
How can I request a sample or quote for Fmoc-Phe(2-Br)-OH?
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To request a sample or a quotation, please contact our sales team via the website or by phone. Provide the product name and CAS number (220497-47-2) for prompt service.
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