4-Ethoxy-3-fluorophenylboronic acid
4-Ethoxy-3-fluorophenylboronic acid (CAS 279263-10-4) is an organoboron compound with the chemical formula C2H5OC6H3(F)B(OH)2 and a molecular weight of 183.97 g/mol. This disubstituted aryl boronic acid serves as a valuable building block in organic synthesis. Its structure, featuring both ethoxy and fluorine substituents on the phenyl ring, allows for diverse reactivity in cross-coupling reactions and other transformations.
- IUPAC
- 4-Ethoxy-3-fluorobenzeneboronic acid
Suzuki-Miyaura Cross-Coupling Reactions
4-Ethoxy-3-fluorophenylboronic acid is commonly employed as a coupling partner in Suzuki-Miyaura reactions, facilitating the formation of carbon-carbon bonds. This enables the synthesis of complex biaryl compounds and functionalised aromatic systems.
Pharmaceutical Intermediate Synthesis
This boronic acid derivative is utilised in the synthesis of advanced pharmaceutical intermediates. Its specific substitution pattern can be incorporated into drug discovery programmes, contributing to the development of novel therapeutic agents.
Material Science Research
The compound finds application in material science for the development of functional organic materials. Its electronic and structural properties can be leveraged in the design of novel polymers, organic electronics, and other advanced materials.
Agrochemical Development
4-Ethoxy-3-fluorophenylboronic acid can serve as a precursor in the synthesis of agrochemical compounds. Its incorporation into molecular scaffolds may lead to the development of new crop protection agents with improved efficacy and selectivity.
| Molecular weight | 183.97 |
|---|---|
| Linear formula | C2H5OC6H3(F)B(OH)2 |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Ethoxy-3-fluorophenylboronic acid used for?
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4-Ethoxy-3-fluorophenylboronic acid is primarily used as a building block in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions for the creation of C-C bonds. It also finds application in the synthesis of pharmaceutical intermediates, agrochemicals, and functional organic materials.
What are the CAS number and chemical formula for this compound?
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The CAS number is 279263-10-4, and the chemical formula is C2H5OC6H3(F)B(OH)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product for research and development purposes. The assay is typically >97%. We do not represent this product as USP, EP, BP, or any other pharmacopoeia grade.
How should 4-Ethoxy-3-fluorophenylboronic acid be handled?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. Use a type N95 (US) or type P1 (EN143) respirator filter if dust is generated. This compound is classified with WGK Germany 3, indicating a high hazard to water.
Is this compound a controlled substance?
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The provided data does not indicate that 4-Ethoxy-3-fluorophenylboronic acid is a controlled substance.
How is 4-Ethoxy-3-fluorophenylboronic acid packed and exported?
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Tech Serve Solutions professionally packs and exports chemicals globally, adhering to all necessary regulations for safe transportation.
How can I request a quote or sample?
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To request a quote or sample, please contact our sales team through the website or by phone, providing the product name and CAS number.
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