Fmoc-β-Homotyr(tBu)-OH
Fmoc-β-Homotyr(tBu)-OH (CAS: 219967-69-8), with the molecular formula C29H31NO5 and a molecular weight of 473.56 g/mol, is a derivative of $\beta$-homotyrosine. This unnatural amino acid derivative is valuable in peptide chemistry and chemical synthesis for its protected tyrosine side chain. It is commonly employed in the construction of modified peptides and peptidomimetics where specific structural or functional alterations are desired, facilitating research in chemical biology.
- IUPAC
- Fmoc-O-tert-butyl-L-β-homotyrosine
- Synonyms
- Fmoc-O-tert-butyl-L-beta-homotyrosine
Peptide Synthesis
Fmoc-β-Homotyr(tBu)-OH serves as a key building block in solid-phase and solution-phase peptide synthesis. Its Fmoc protecting group allows for facile deprotection under mild basic conditions, enabling controlled chain elongation.
Chemical Biology Research
This compound is utilised in the creation of peptides with modified structures for investigating biological pathways and protein interactions. The incorporation of unnatural amino acids like this can impart unique properties to peptide-based probes.
Drug Discovery and Development
As a component in the synthesis of peptidomimetics, Fmoc-β-Homotyr(tBu)-OH aids in the development of novel therapeutic agents. These molecules often exhibit improved stability and bioavailability compared to their natural peptide counterparts.
Material Science
Modified peptides incorporating unnatural amino acids can be explored for their self-assembly properties and potential applications in biomaterials and nanotechnology.
| Molecular weight | 473.56 |
|---|---|
| Empirical formula | C29H31NO5 |
| Assay | ≥98.0% |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-β-Homotyr(tBu)-OH used for?
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Fmoc-β-Homotyr(tBu)-OH is primarily used as a protected building block in peptide synthesis, chemical biology research, and the development of peptidomimetics and novel therapeutic agents.
What are the CAS number and molecular formula for Fmoc-β-Homotyr(tBu)-OH?
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The CAS number for Fmoc-β-Homotyr(tBu)-OH is 219967-69-8, and its molecular formula is C29H31NO5.
What grade and purity does Tech Serve Solutions supply for Fmoc-β-Homotyr(tBu)-OH?
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Tech Serve Solutions supplies Fmoc-β-Homotyr(tBu)-OH with an assay of $\ge$98.0%. This product is intended for research and laboratory use. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Fmoc-β-Homotyr(tBu)-OH be handled and stored?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves, and potentially a type N95 (US) or P1 (EN143) respirator filter. It should be stored at 2-8°C to maintain its integrity. The compound has a WGK Germany classification of 3.
Is Fmoc-β-Homotyr(tBu)-OH a controlled substance?
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The provided data does not indicate that Fmoc-β-Homotyr(tBu)-OH is a controlled substance.
How can I request a sample or quote for Fmoc-β-Homotyr(tBu)-OH?
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To request a sample or a quote for Fmoc-β-Homotyr(tBu)-OH, please contact the Tech Serve Solutions sales department via our website or by phone.
How is Fmoc-β-Homotyr(tBu)-OH packed and exported?
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Fmoc-β-Homotyr(tBu)-OH is carefully packed to ensure stability during transport and is available for global export by Tech Serve Solutions, a specialist supplier since 1998.
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