Fmoc-β-Homotrp-OH
Fmoc-β-Homotrp-OH (CAS 353245-98-4), a derivative of the unnatural amino acid Nβ-Fmoc-L-β-homotryptophan, is a key building block in peptide synthesis. With the molecular formula C27H24N2O4 and a molecular weight of 440.49 g/mol, this compound is essential for constructing modified peptides and peptidomimetics. It plays a crucial role in chemical biology and synthesis, enabling the exploration of novel biomolecular structures and functions.
- IUPAC
- (S)-3-(Fmoc-amino)-4-(3-indolyl)butyricacid,Nβ-Fmoc-L-β-homotryptophan

Peptide Synthesis
Used as a protected unnatural amino acid for solid-phase or solution-phase peptide synthesis. Facilitates the incorporation of beta-amino acid residues into peptide chains to introduce specific structural features or improve stability.
Chemical Biology Research
Enables the design and synthesis of peptides with altered conformations or enhanced biological activity. Useful for probing protein-protein interactions and developing peptide-based therapeutics.
Organic Synthesis
Serves as a versatile intermediate in the synthesis of complex organic molecules, particularly those incorporating indole and amino acid functionalities.
| Molecular weight | 440.49 |
|---|---|
| Empirical formula | C27H24N2O4 |
| Assay | ≥96.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-β-Homotrp-OH used for?
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Fmoc-β-Homotrp-OH is primarily used as a protected unnatural amino acid in peptide synthesis and chemical biology research to create modified peptides and peptidomimetics.
What is the CAS number and formula for Fmoc-β-Homotrp-OH?
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The CAS number is 353245-98-4 and the empirical formula is C27H24N2O4.
What grade and purity does Tech Serve Solutions supply for Fmoc-β-Homotrp-OH?
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Tech Serve Solutions supplies Fmoc-β-Homotrp-OH with a purity of ≥96.0% (HPLC). This product is suitable for research and chemical synthesis purposes and is not represented as USP, BP, or EP grade.
How should Fmoc-β-Homotrp-OH be handled and stored?
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Handle Fmoc-β-Homotrp-OH with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Store at 2-8°C.
Is Fmoc-β-Homotrp-OH a controlled substance?
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Based on the provided data, Fmoc-β-Homotrp-OH is not indicated as a controlled substance.
How is Fmoc-β-Homotrp-OH packed and shipped?
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This chemical is typically packed for laboratory use and can be exported globally by Tech Serve Solutions, adhering to all relevant shipping regulations.
How can I request a sample or quote for Fmoc-β-Homotrp-OH?
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To request a sample or quote, please contact the Tech Serve Solutions sales department through our website or by calling our customer service line.
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