Fmoc-β-Homoser(tBu)-OH
Fmoc-β-Homoser(tBu)-OH (CAS: 203854-51-7), with the molecular formula C23H27NO5 and a molecular weight of 397.46 g/mol, is a protected unnatural amino acid derivative. It is an essential building block utilised in peptide chemistry and chemical synthesis. This compound is particularly valuable for incorporating non-proteinogenic amino acids into peptide chains, expanding the scope of biochemical research and drug discovery.
- IUPAC
- Fmoc-O-tert-butyl-L-β-homoserine

Peptide Synthesis
Fmoc-β-Homoser(tBu)-OH serves as a key intermediate in the synthesis of peptides containing unnatural beta-amino acid residues. Its Fmoc protecting group allows for controlled solid-phase or solution-phase peptide assembly.
Chemical Biology Research
This compound enables the introduction of modified amino acid structures into biomolecules. Researchers utilise it to study protein function, develop novel therapeutic peptides, and probe biological pathways.
Drug Discovery and Development
As a building block for peptidomimetics and modified peptides, Fmoc-β-Homoser(tBu)-OH contributes to the development of new pharmaceutical agents with enhanced stability or specific biological activity.
Organic Synthesis
Beyond peptide chemistry, this beta-amino acid derivative can be employed in various organic synthesis strategies requiring its specific functional groups and chiral centre.
| Molecular weight | 397.46 |
|---|---|
| Empirical formula | C23H27NO5 |
| Assay | ≥97.5% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-β-Homoser(tBu)-OH used for?
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Fmoc-β-Homoser(tBu)-OH is used as a protected unnatural beta-amino acid building block in peptide synthesis, chemical biology research, and drug discovery.
What is the CAS number and chemical formula for Fmoc-β-Homoser(tBu)-OH?
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The CAS number for Fmoc-β-Homoser(tBu)-OH is 203854-51-7, and its chemical formula is C23H27NO5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-β-Homoser(tBu)-OH with an assay of ≥97.5% (HPLC). TSS does not represent this product as USP, BP, EP, or any other pharmacopoeial grade.
How should Fmoc-β-Homoser(tBu)-OH be handled and stored?
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Handle Fmoc-β-Homoser(tBu)-OH with appropriate personal protective equipment, including eyeshields and gloves. A respirator filter such as type N95 (US) or P1 (EN143) is recommended. Store the compound at 2-8°C.
Is Fmoc-β-Homoser(tBu)-OH a controlled substance?
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The provided data does not indicate that Fmoc-β-Homoser(tBu)-OH is a controlled substance.
How is Fmoc-β-Homoser(tBu)-OH packed and shipped?
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Fmoc-β-Homoser(tBu)-OH is carefully packed to maintain its integrity during transport and is exported globally by Tech Serve Solutions.
How can I request a quote or sample for Fmoc-β-Homoser(tBu)-OH?
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To request a quote or a sample of Fmoc-β-Homoser(tBu)-OH, please contact the Tech Serve Solutions sales team through the website or by phone.
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