Fmoc-β-Homolys(Boc)-OH
Fmoc-β-Homolys(Boc)-OH (CAS: 203854-47-1) is a protected unnatural beta-amino acid derivative with the empirical formula C27H34N2O6 and a molecular weight of 482.57 g/mol. This compound is primarily utilised in specialised chemical synthesis, particularly within peptide chemistry and chemical biology research. Its structure lends itself to the incorporation of modified amino acid residues into peptides, enabling the exploration of novel structures and functionalities in biochemical studies.
- IUPAC
- (S)-7-(Boc-amino)-3-(Fmoc-amino)heptanoic acid,Nβ-Fmoc-Nω-Boc-L-β-homolysine

Peptide Synthesis
Utilised as a building block in solid-phase or solution-phase peptide synthesis for creating peptides with modified backbones or side chains. It allows for the introduction of a beta-homolysine residue with orthogonal protection strategies.
Chemical Biology Research
Serves as a tool in chemical biology for constructing peptides or peptidomimetics with altered conformational properties or biological activities. Its unnatural structure can be used to probe protein-protein interactions or develop novel therapeutic agents.
Drug Discovery and Development
Incorporated into lead compounds during the drug discovery process to enhance stability, bioavailability, or target engagement. The beta-amino acid motif can offer advantages over natural alpha-amino acids in certain pharmacological contexts.
Unnatural Amino Acid Derivatisation
A key reagent for chemists working with unnatural amino acid derivatives, offering a protected form of beta-homolysine for incorporation into complex molecular architectures.
| Molecular weight | 482.57 |
|---|---|
| Empirical formula | C27H34N2O6 |
| Assay | ≥95.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-β-Homolys(Boc)-OH used for?
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Fmoc-β-Homolys(Boc)-OH is primarily used in specialised chemical synthesis, particularly in peptide chemistry and chemical biology research, for the incorporation of unnatural amino acid residues into peptides and peptidomimetics.
What is the CAS number and chemical formula for Fmoc-β-Homolys(Boc)-OH?
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The CAS number is 203854-47-1 and the empirical formula is C27H34N2O6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-β-Homolys(Boc)-OH with a purity of ≥95.0% as determined by HPLC. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Fmoc-β-Homolys(Boc)-OH be handled and stored?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. Use a P1 (EN143) or N95 (US) respirator if necessary. Store refrigerated between 2-8°C.
Is Fmoc-β-Homolys(Boc)-OH a controlled substance?
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The provided safety data does not indicate that Fmoc-β-Homolys(Boc)-OH is a controlled substance.
How is this chemical packed, shipped, and exported?
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This chemical is carefully packed according to industry standards for safe transport and is available for global export by Tech Serve Solutions.
How can I request a quote or sample of Fmoc-β-Homolys(Boc)-OH?
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Please contact our sales department via the website or by phone to request a quotation or to arrange for a sample.
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