Fmoc-β-Homoglu(OtBu)-OH
Fmoc-β-Homoglu(OtBu)-OH (CAS: 203854-49-3), with the molecular formula C25H29NO6 and a molecular weight of 439.50 g/mol, is a protected unnatural amino acid derivative. This compound is a valuable building block primarily utilised in peptide synthesis and chemical biology research. Its structure incorporates the Fmoc protecting group for amine functionality and a tert-butyl ester for the carboxylic acid, facilitating controlled solid-phase or solution-phase peptide coupling reactions.
- IUPAC
- (S)-3-(Fmoc-amino)adipic acid 6-tert-butyl ester,Fmoc-L-β-homoglutamic acid 6-tert-butyl ester
Peptide Synthesis
Fmoc-β-Homoglu(OtBu)-OH serves as a key intermediate in the synthesis of peptides containing beta-homoglutamic acid residues. The Fmoc protecting group allows for orthogonal deprotection strategies in solid-phase peptide synthesis (SPPS).
Chemical Biology
This unnatural amino acid derivative is employed in chemical biology to introduce modified amino acid functionalities into peptides and proteins. This enables the study of peptide structure-activity relationships and the development of novel biomaterials.
Organic Synthesis
The compound's protected functional groups make it a versatile reagent in complex organic synthesis, particularly for constructing molecules with specific stereochemistry and functional group arrangements.
| Molecular weight | 439.50 |
|---|---|
| Empirical formula | C25H29NO6 |
| Assay | ≥96.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-β-Homoglu(OtBu)-OH used for?
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Fmoc-β-Homoglu(OtBu)-OH is primarily used in peptide synthesis and chemical biology as a building block for incorporating unnatural beta-homoglutamic acid residues into peptide chains.
What are the CAS number and molecular formula of Fmoc-β-Homoglu(OtBu)-OH?
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The CAS number for Fmoc-β-Homoglu(OtBu)-OH is 203854-49-3, and its molecular formula is C25H29NO6.
What grade and purity does Tech Serve Solutions supply for Fmoc-β-Homoglu(OtBu)-OH?
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Tech Serve Solutions supplies Fmoc-β-Homoglu(OtBu)-OH with a purity of ≥96.0% (HPLC). TSS does not represent this product as USP, BP, EP, or other pharmacopoeial grades unless explicitly stated.
How should Fmoc-β-Homoglu(OtBu)-OH be handled and stored?
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Handle Fmoc-β-Homoglu(OtBu)-OH with appropriate personal protective equipment, including eyeshields and gloves. Respiratory protection with a type N95 (US) or type P1 (EN143) respirator filter is recommended. Store at 2-8°C.
Is Fmoc-β-Homoglu(OtBu)-OH a controlled substance?
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The provided data does not indicate that Fmoc-β-Homoglu(OtBu)-OH is a controlled substance. It is classified under WGK Germany 3.
How is Fmoc-β-Homoglu(OtBu)-OH packed and shipped?
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This chemical is carefully packed according to industry standards to ensure safe transit and is available for global export by Tech Serve Solutions.
How can I request a sample or quote for Fmoc-β-Homoglu(OtBu)-OH?
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To request a sample or a quotation for Fmoc-β-Homoglu(OtBu)-OH, please contact the Tech Serve Solutions sales team through our website or by phone.
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