Fmoc-β-Homohyp(tBu)-OH
Fmoc-β-Homohyp(tBu)-OH (CAS: 957509-29-4) is a protected unnatural amino acid derivative with the molecular formula C25H29NO5 and a molecular weight of 423.50. This compound serves as a valuable building block in peptide synthesis and chemical biology research. It is particularly useful for incorporating beta-homoproline residues into peptide chains, enabling the study of peptide structure, function, and the development of novel biomolecules.
- IUPAC
- Fmoc-O-tert-butyl-L-β-homohydroxyproline
- Synonyms
- Fmoc-O-tert-butyl-L-beta-homoproline
Peptide Synthesis
Fmoc-β-Homohyp(tBu)-OH is utilised in solid-phase and solution-phase peptide synthesis. Its Fmoc protecting group allows for orthogonal deprotection strategies, facilitating the construction of complex peptide sequences incorporating unnatural beta-amino acids.
Chemical Biology Research
This unnatural amino acid derivative is employed to explore the impact of beta-homoproline residues on peptide conformation and biological activity. It aids in designing peptides with enhanced stability or novel therapeutic properties.
Drug Discovery and Development
As a building block, it contributes to the synthesis of peptidomimetics and modified peptides for potential pharmaceutical applications, aiding in the search for new drug candidates.
Custom Synthesis
It serves as a key intermediate in custom synthesis projects requiring the incorporation of specific beta-amino acid structures into larger molecules.
| Molecular weight | 423.50 |
|---|---|
| Empirical formula | C25H29NO5 |
| Assay | ≥98.0% |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-β-Homohyp(tBu)-OH used for?
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Fmoc-β-Homohyp(tBu)-OH is primarily used as a building block in peptide synthesis and for research in chemical biology and drug discovery, allowing for the incorporation of unnatural beta-homoproline residues into peptide structures.
What are the CAS number and formula for Fmoc-β-Homohyp(tBu)-OH?
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The CAS number is 957509-29-4, and the empirical formula (Hill notation) is C25H29NO5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-β-Homohyp(tBu)-OH with an assay of ≥98.0%. This product is intended for research purposes and is not represented as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling recommendations for Fmoc-β-Homohyp(tBu)-OH?
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Appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter, should be used when handling this compound. It has a WGK rating of 3 in Germany, indicating a high hazard to water.
How is Fmoc-β-Homohyp(tBu)-OH typically shipped and stored?
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This product is typically shipped and exported according to standard chemical handling procedures. For optimal stability, it should be stored at 2-8°C.
How can I request a sample or quote for Fmoc-β-Homohyp(tBu)-OH?
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To request a sample or a quote for Fmoc-β-Homohyp(tBu)-OH, please contact our sales department through the website or by telephone.
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