Fmoc-β-Homoile-OH
Fmoc-β-Homoile-OH (CAS: 193954-27-7) is a protected unnatural beta-amino acid derivative with the molecular formula C22H25NO4 and a molecular weight of 367.44 g/mol. It is a valuable building block in peptide synthesis and chemical biology research. This compound is essential for introducing non-proteinogenic amino acid residues into peptide chains, enabling the exploration of novel peptide structures and functionalities in various chemical synthesis applications.
- IUPAC
- (3R,4S)-3-(Fmoc-amino)-4-methylhexanoic acid,Fmoc-L-β-homoisoleucine

Peptide Synthesis
Fmoc-β-Homoile-OH serves as a key intermediate for incorporating unnatural beta-amino acid residues into peptide sequences. This allows for the creation of peptides with modified backbones, potentially leading to enhanced stability or novel biological activities.
Chemical Biology Research
This unnatural amino acid derivative is utilised in chemical biology to probe protein structure-function relationships or to design peptidomimetics. Its unique structure can confer distinct properties compared to natural amino acids.
Organic Synthesis
As a specialised building block, Fmoc-β-Homoile-OH is employed in complex organic synthesis pathways. Its Fmoc protecting group facilitates controlled coupling reactions in multi-step synthetic procedures.
| Molecular weight | 367.44 |
|---|---|
| Empirical formula | C22H25NO4 |
| Assay | ≥96.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-β-Homoile-OH used for?
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Fmoc-β-Homoile-OH is primarily used as a building block in peptide synthesis and in chemical biology research for creating peptides with unnatural beta-amino acid residues. It is also utilised in general organic synthesis.
What are the CAS number and chemical formula for Fmoc-β-Homoile-OH?
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The CAS number for Fmoc-β-Homoile-OH is 193954-27-7, and its empirical formula is C22H25NO4.
What grade and purity does Tech Serve Solutions supply for Fmoc-β-Homoile-OH?
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Tech Serve Solutions supplies Fmoc-β-Homoile-OH with an assay of ≥96.0% (HPLC). We do not represent this product as USP, BP, EP, or for pharmaceutical use.
How should Fmoc-β-Homoile-OH be handled and stored?
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Handle Fmoc-β-Homoile-OH with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter may be required. It should be stored at refrigerated temperatures between 2-8°C.
Is Fmoc-β-Homoile-OH a controlled substance?
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The provided data does not indicate that Fmoc-β-Homoile-OH is a controlled substance.
How can I request a quote or sample for Fmoc-β-Homoile-OH?
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Please contact our sales team via the website to request a quote or to inquire about obtaining a sample of Fmoc-β-Homoile-OH.
How is Fmoc-β-Homoile-OH packed, shipped, and exported?
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Fmoc-β-Homoile-OH is carefully packed to ensure stability during transit. As a global supplier, Tech Serve Solutions has extensive experience in exporting fine chemicals worldwide, adhering to all relevant shipping regulations.
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