Fmoc-β-Homophe-OH
Fmoc-β-Homophe-OH (CAS: 193954-28-8), a derivative of the unnatural amino acid phenylalanine, is a key building block in peptide synthesis. With the molecular formula C25H23NO4, this compound features the Fmoc protecting group, facilitating controlled peptide chain elongation. It is primarily utilised in the construction of modified peptides and peptidomimetics for research in chemical biology and drug discovery.
- IUPAC
- (S)-3-(Fmoc-amino)-4-phenylbutyric acid,Fmoc-L-β-homophenylalanine
Peptide Synthesis
Fmoc-β-Homophe-OH is used as a protected unnatural amino acid for incorporating beta-homophenylalanine residues into peptide chains via solid-phase or solution-phase synthesis. This enables the creation of peptides with altered conformational properties or biological activity.
Chemical Biology Research
This compound serves as a valuable tool for researchers investigating the structure-activity relationships of peptides. Its incorporation can probe the effects of beta-amino acid substitution on peptide folding, stability, and receptor binding.
Drug Discovery and Development
Fmoc-β-Homophe-OH is employed in the synthesis of novel peptidomimetics and modified peptides explored for therapeutic applications. The unnatural beta-amino acid structure can impart unique pharmacokinetic or pharmacodynamic properties.
| Molecular weight | 401.45 |
|---|---|
| Empirical formula | C25H23NO4 |
| Assay | ≥95.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-β-Homophe-OH used for?
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Fmoc-β-Homophe-OH is used in peptide synthesis, chemical biology research, and drug discovery for creating modified peptides and peptidomimetics incorporating unnatural beta-amino acid residues.
What are the CAS number and formula for Fmoc-β-Homophe-OH?
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The CAS number for Fmoc-β-Homophe-OH is 193954-28-8, and its empirical formula is C25H23NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-β-Homophe-OH with a purity of ≥95.0% as determined by HPLC. This product is intended for research purposes and is not supplied as USP, BP, EP, or pharmacopoeia grade.
How should Fmoc-β-Homophe-OH be handled and stored?
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Fmoc-β-Homophe-OH should be stored at 2-8°C. When handling, it is recommended to use safety equipment including eyeshields, gloves, and a type N95 (US) or P1 (EN143) respirator filter, as indicated by its safety data.
Is Fmoc-β-Homophe-OH a controlled substance?
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The provided data does not indicate that Fmoc-β-Homophe-OH is a controlled substance.
How is Fmoc-β-Homophe-OH packed, shipped, and exported?
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Fmoc-β-Homophe-OH is available from Tech Serve Solutions, a global supplier and exporter of fine chemicals. Packaging and shipping methods comply with international regulations for chemical transport.
How can I request a sample or quote for Fmoc-β-Homophe-OH?
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To request a sample or a quote for Fmoc-β-Homophe-OH, please contact the Tech Serve Solutions sales team through our website or by phone.
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