Fmoc-β-Leu-OH
Fmoc-β-Leu-OH (CAS: 172695-33-9), a key unnatural amino acid derivative, is supplied by Tech Serve Solutions. With the empirical formula C21H23NO4 and a molecular weight of 353.41 g/mol, this compound is essential in peptide chemistry and synthesis. Its structure, featuring the Fmoc protecting group, facilitates controlled peptide elongation. It finds applications in chemical biology for creating novel peptide structures and in the development of pharmaceutical intermediates.
- IUPAC
- (R)-3-(Fmoc-amino)-4-methylpentanoic acid,Fmoc-L-β-homovaline,Fmoc-L-β-leucine

Peptide Synthesis
Fmoc-β-Leu-OH is a valuable building block in solid-phase and solution-phase peptide synthesis. It allows for the introduction of beta-amino acids into peptide sequences, expanding the structural diversity and potential therapeutic applications of synthetic peptides.
Chemical Biology Research
This unnatural amino acid derivative is utilised in chemical biology to design and synthesise peptides with modified backbones. These modifications can lead to peptides with enhanced stability, altered biological activity, or novel functionalities for research purposes.
Pharmaceutical Intermediate Development
As a specialised chemical intermediate, Fmoc-β-Leu-OH plays a role in the multi-step synthesis of complex pharmaceutical compounds. Its incorporation can contribute to the development of novel drug candidates with unique pharmacological profiles.
Unnatural Amino Acid Derivatives
Fmoc-β-Leu-OH belongs to a class of unnatural amino acid derivatives crucial for advancing organic and medicinal chemistry. Researchers use these compounds to explore non-natural peptide structures and their potential biological or material science applications.
| Molecular weight | 353.41 |
|---|---|
| Empirical formula | C21H23NO4 |
| Assay | ≥97.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-β-Leu-OH used for?
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Fmoc-β-Leu-OH is primarily used as a building block in peptide synthesis, chemical biology research, and the development of pharmaceutical intermediates due to its unnatural beta-amino acid structure and Fmoc protecting group.
What are the CAS number and formula for Fmoc-β-Leu-OH?
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The CAS number for Fmoc-β-Leu-OH is 172695-33-9, and its empirical formula is C21H23NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-β-Leu-OH with a purity of ≥97.0% by HPLC. This compound is supplied for research and development purposes and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should Fmoc-β-Leu-OH be handled and stored?
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Handle Fmoc-β-Leu-OH with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Store the material at 2-8°C to maintain its integrity.
Is Fmoc-β-Leu-OH a controlled substance?
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The provided data does not indicate that Fmoc-β-Leu-OH is a controlled substance.
How is Fmoc-β-Leu-OH packed, shipped, and exported?
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Tech Serve Solutions, a global supplier and exporter, packs and ships fine chemicals like Fmoc-β-Leu-OH according to industry standards for safe transport, including international export requirements.
How can I request a sample or quote for Fmoc-β-Leu-OH?
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To request a sample or quote for Fmoc-β-Leu-OH, please contact our sales team through the website or direct inquiry channels provided by Tech Serve Solutions.
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