Fmoc-Homoser(Trt)-OH
Fmoc-Homoser(Trt)-OH (CAS: 111061-55-3) is a protected amino acid derivative with the empirical formula C38H33NO5 and a molecular weight of 583.67 g/mol. It is commonly employed in peptide synthesis and chemical biology research. Its structure incorporates the Fmoc protecting group for amine functionality and a trityl group for side-chain protection, facilitating controlled peptide chain elongation. This compound is essential for incorporating unnatural amino acid residues into peptides.
- IUPAC
- Nα-Fmoc-O-trityl-L-homoserine

Peptide Synthesis
Fmoc-Homoser(Trt)-OH serves as a crucial building block in solid-phase and solution-phase peptide synthesis. The Fmoc group allows for facile deprotection under mild basic conditions, enabling sequential coupling reactions.
Chemical Biology
This unnatural amino acid derivative is utilised in chemical biology to introduce modified residues into peptides, enabling the study of protein function, structure, and interactions.
Custom Peptide Development
Researchers developing custom peptides for therapeutic or diagnostic applications can utilise Fmoc-Homoser(Trt)-OH to incorporate specific structural modifications.
| Molecular weight | 583.67 |
|---|---|
| Empirical formula | C38H33NO5 |
| Assay | ≥98.0% (HPLC) |
| Storage temperature | 2-8°C |
| Impurities tested | ≤15 wt. % Ethanol, may contain |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Homoser(Trt)-OH used for?
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Fmoc-Homoser(Trt)-OH is primarily used as a building block in peptide synthesis and chemical biology research for the incorporation of unnatural amino acid residues.
What is the CAS number and molecular formula for Fmoc-Homoser(Trt)-OH?
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The CAS number is 111061-55-3 and the molecular formula is C38H33NO5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-Homoser(Trt)-OH with an assay of ≥98.0% (HPLC). This product is not represented as USP, BP, or EP grade.
What are the safety and handling recommendations for Fmoc-Homoser(Trt)-OH?
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Appropriate personal protective equipment including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter should be used when handling. The product has a WGK Germany rating of 3.
How is Fmoc-Homoser(Trt)-OH packed and shipped?
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Fmoc-Homoser(Trt)-OH is typically stored at 2-8°C. TSS exports chemicals globally, ensuring appropriate packaging for safe transport.
How can I request a sample or quote for Fmoc-Homoser(Trt)-OH?
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Please contact our sales team via the website to request a sample or a formal quotation for Fmoc-Homoser(Trt)-OH.
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