Fmoc-Homophe-OH
Fmoc-Homophe-OH (CAS: 132684-59-4), with the empirical formula C25H23NO4 and a molecular weight of 401.45 g/mol, is a key derivative in peptide chemistry. This unnatural amino acid derivative is primarily utilised in chemical synthesis and chemical biology for the construction of peptides and peptidomimetics, enabling the introduction of modified amino acid residues into peptide chains.
- IUPAC
- (S)-2-(Fmoc-amino)-4-phenylbutyric acid,Fmoc-L-homophenylalanine

Peptide Synthesis
Fmoc-Homophe-OH serves as a protected unnatural amino acid for incorporation into peptide sequences using solid-phase or solution-phase synthesis methodologies. Its unique structure allows for modifications to peptide backbones and side chains.
Chemical Biology Research
This compound is employed in chemical biology to create modified peptides or proteins for studying biological processes. It aids in developing probes or analogues with altered properties compared to natural amino acids.
Drug Discovery and Development
As a building block in medicinal chemistry, Fmoc-Homophe-OH can be used to synthesise novel peptidomimetics or modified peptides with potential therapeutic applications. This contributes to the development of new drug candidates.
| Molecular weight | 401.45 |
|---|---|
| Empirical formula | C25H23NO4 |
| Assay | ≥98.0% |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Homophe-OH primarily used for?
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Fmoc-Homophe-OH is primarily used in peptide synthesis, chemical biology, and drug discovery as a protected unnatural amino acid derivative for building modified peptides and peptidomimetics.
What are the CAS number and empirical formula for Fmoc-Homophe-OH?
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The CAS number for Fmoc-Homophe-OH is 132684-59-4, and its empirical formula is C25H23NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-Homophe-OH with an assay of ≥98.0%. We do not represent this product as USP, BP, or EP grade.
How should Fmoc-Homophe-OH be handled and stored?
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Fmoc-Homophe-OH should be handled with appropriate personal protective equipment, including eyeshields and gloves. It requires refrigerated storage at 2-8°C. It has a WGK Germany rating of 3.
Is Fmoc-Homophe-OH a controlled substance?
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The provided data does not indicate that Fmoc-Homophe-OH is a controlled substance.
How is Fmoc-Homophe-OH packed, shipped, and exported?
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Fmoc-Homophe-OH is carefully packed to ensure stability during transit and is available for global export by Tech Serve Solutions.
How can I request a sample or quote for Fmoc-Homophe-OH?
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To request a sample or a quote for Fmoc-Homophe-OH, please contact the Tech Serve Solutions sales team through our website or by phone.
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