Fmoc-Ile-OH
N-(9-Fluorenylmethoxycarbonyl)-L-isoleucine (CAS: 71989-23-6; C21H23NO4) is a protected amino acid derivative with a molecular weight of 353.41 g/mol. It is a key building block in solid-phase peptide synthesis (SPPS), facilitating the controlled elongation of peptide chains. Its primary application lies in the research and development of peptides for pharmaceutical and biochemical applications.
- IUPAC
- N-(9-Fluorenylmethoxycarbonyl)-L-isoleucine,Fmoc-L-isoleucine
- Synonyms
- N-(9-Fluorenylmethoxycarbonyl)-L-isoleucine
Peptide Synthesis Reagent
Fmoc-Ile-OH is extensively used as a protected isoleucine residue in solid-phase peptide synthesis. The Fmoc protecting group allows for orthogonal deprotection strategies, crucial for constructing complex peptide sequences.
Biochemical Research
It serves as a valuable tool in biochemical research for the synthesis of peptides with specific biological activities or structural properties, aiding in the study of protein function and interactions.
Drug Discovery and Development
In drug discovery, Fmoc-Ile-OH is employed in the synthesis of peptide-based therapeutics and drug candidates, contributing to the development of novel treatments.
| Molecular weight | 353.41 |
|---|---|
| Empirical formula | C21H23NO4 |
| Assay | ≥98.0% (T) |
| Optical activity | [α]20/D −12±1°, c = 1% in DMF |
| Storage temperature | 2-8°C |
| Melting point | 145-147 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Ile-OH used for?
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Fmoc-Ile-OH is primarily used as a building block in solid-phase peptide synthesis (SPPS) for the controlled elongation of peptide chains in research and development settings.
What is the CAS number and chemical formula for Fmoc-Ile-OH?
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The CAS number is 71989-23-6 and the chemical formula is C21H23NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-Ile-OH with an assay of ≥98.0% (T). This is a research-grade chemical and is not represented as USP, BP, or EP.
What are the safety and handling recommendations for Fmoc-Ile-OH?
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Handle Fmoc-Ile-OH with appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or P1 (EN143) respirator filter. It has a melting point of 145-147°C.
How is Fmoc-Ile-OH packed, shipped, and exported?
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Fmoc-Ile-OH is typically stored at 2-8°C. Tech Serve Solutions exports fine chemicals globally, adhering to all relevant shipping regulations.
How can I request a sample or quote for Fmoc-Ile-OH?
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Please contact our sales team via the website or direct inquiry to request a sample or a quotation for Fmoc-Ile-OH.
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