Nitrosobenzene

CAS 586-96-9C6H5NOOrganic Building Blocks

Nitrosobenzene (CAS: 586-96-9), with the molecular formula C6H5NO and a molar mass of 107.11 g/mol, is a nitroso compound. This chemical serves as a valuable spin trap reagent, finding utility in scientific research for studying oxidative DNA damage. Its applications extend to investigating the nitroso-compound-induced respiratory burst in neutrophils, making it a key material for biochemical and toxicological investigations.

IUPAC: NOB

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Nitrosobenzene (C6H5NO) — chemical structure, CAS 586-96-9; Chemistry, fine chemical supplied by Tech Serve Solutions

Building BlocksChemical SynthesisNitrogen CompoundsNitroso CompoundsOrganic Building Blocks

01 /Applications

Spin Trapping Agent

Nitrosobenzene is employed as a spin trap reagent in chemical and biological research. It is used to detect and identify transient free radicals by forming more stable adducts, facilitating their study.

Oxidative DNA Damage Studies

This compound has been utilised in the investigation of oxidative DNA damage. Its properties allow researchers to explore mechanisms by which reactive species can interact with genetic material.

Neutrophil Respiratory Burst Research

Nitrosobenzene is used in studies examining the respiratory burst in neutrophils. It aids in understanding the signalling pathways and reactive oxygen species involved in cellular immune responses.

02 /Properties

Molecular weight	107.11
Empirical formula	C6H5NO
Assay	≥97.5% (GC)
Boiling point	59 °C/18 mmHg(lit.)
Storage temperature	2-8°C
Application	Spin trap reagent. Has been used in the study of oxidative DNA damage and nitroso-compound-induced respiratory burst in neutrophils1,2.
Melting point	65-69 °C(lit.)65-69 °C

03 /Safety & handling

GHS hazard pictogram: Toxic (GHS06) — Toxic

Danger

Hazard statements

H301Toxic if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled

Precautionary statements

P280Wear protective gloves, clothing and eye/face protection
P301IF SWALLOWED

Protective equipment	Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Transport (UN / ADR)	UN 2811 6.1 / PGIII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	T
Risk statements (R)	20/21-25
Safety statements (S)	26-36/37-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

586-96-9

MDL number

MFCD00002059

PubChem substance

24886616

Beilstein registry

605688

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Nitrosobenzene (CAS 586-96-9) used for?

Nitrosobenzene (CAS 586-96-9) is primarily used as a spin trap reagent in research, particularly for studying oxidative DNA damage and the nitroso-compound-induced respiratory burst in neutrophils.

What are the CAS number and molecular formula for Nitrosobenzene?

The CAS number for Nitrosobenzene is 586-96-9, and its molecular formula is C6H5NO.

What grade and purity does Tech Serve Solutions supply for Nitrosobenzene?

Tech Serve Solutions supplies Nitrosobenzene with an assay of ≥97.5% (GC). We do not represent this product as USP, BP, EP or any other pharmacopoeia grade.

How should Nitrosobenzene be handled safely?

Nitrosobenzene is a dangerous substance (GHS06, Danger). It is toxic if swallowed (H301), toxic in contact with skin (H312), and toxic if inhaled (H332). Handle with appropriate personal protective equipment, including eyeshields, faceshields, gloves, and P2 respirator cartridges. Ensure adequate ventilation and follow safety statements P280 and P301 + P310.

Is Nitrosobenzene packed and shipped internationally by TSS?

Yes, Tech Serve Solutions specialises in the global supply and export of fine chemicals like Nitrosobenzene, adhering to all necessary transport regulations (UN 2811 6.1 / PGIII).