Prion Protein Fragment 106-126 Human
Prion Protein Fragment 106-126 Human (CAS: 148439-49-0), with the empirical formula C80H138N26O24S2 and a molecular weight of 1912.24 g/mol, is a synthetic peptide fragment of the human prion protein. This compound serves as a critical research tool for investigating the mechanisms of neurodegeneration associated with prion diseases, including Amyotrophic Lateral Sclerosis (ALS) and Creutzfeldt-Jakob disease, by mimicking the aggregation and toxicity of misfolded prion proteins.
- IUPAC
- PrP [106-126]
Neurodegenerative Disease Research
Utilized as a model peptide to study the pathological processes underlying prion diseases. It helps researchers understand protein misfolding, aggregation, and cellular toxicity relevant to conditions like ALS and other prion-related encephalopathies.
Cell Biology Studies
Applied in cell-based assays to investigate cellular responses to prion protein fragments. This includes studying mechanisms of cell death, stress pathways, and the interaction of misfolded proteins with cellular components.
Neuroscience and Cell Signaling
Employed in neuroscience research to explore pathways involved in neurodegeneration and cell signaling disruptions caused by prion protein aggregation. It aids in the development of potential therapeutic targets.
| Molecular weight | 1912.24 |
|---|---|
| Empirical formula | C80H138N26O24S2 |
| Assay | ≥90% (HPLC) |
| Form | solid |
| Storage temperature | −20°C |
| Application | Used as a model to investigate neurodegeneration in prion diseases. |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... PRNP(5621) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Prion Protein Fragment 106-126 Human used for?
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This fragment is used as a model to investigate neurodegeneration in prion diseases, including ALS. It is also applied in cell biology and neuroscience research to study cellular responses and signaling pathways affected by prion protein aggregation.
What are the CAS number and formula for Prion Protein Fragment 106-126 Human?
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The CAS number is 148439-49-0 and the empirical formula is C80H138N26O24S2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Prion Protein Fragment 106-126 Human with a purity of ≥90% (HPLC). This product is supplied for research purposes and is not intended for human or veterinary use, nor is it represented as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling recommendations for this product?
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When handling Prion Protein Fragment 106-126 Human, it is essential to wear eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. The compound has a WGK rating of 3 in Germany, indicating a high hazard.
How is Prion Protein Fragment 106-126 Human typically stored and shipped?
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This product should be stored at -20°C. For export and shipment, it is packaged according to international regulations for fine chemicals.
How can I request a sample or quote for Prion Protein Fragment 106-126 Human?
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To request a sample or a quotation for Prion Protein Fragment 106-126 Human, please contact our sales department via the website or by phone.
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