Fmoc-L-β3-homoproline
Fmoc-L-β3-homoproline (CAS: 193693-60-6), with the molecular formula C21H21NO4 and a molecular weight of 351.40, is a specialised unnatural amino acid derivative. It is primarily employed in chemical synthesis and peptide chemistry. This compound serves as a valuable building block in the development of novel peptides and peptidomimetics, contributing to advancements in chemical biology research and drug discovery.
- IUPAC
- (S)-2-(1-Fmoc-2-pyrrolidinyl)acetic acid

Peptide Synthesis
Fmoc-L-β3-homoproline is utilised as a non-natural building block in solid-phase and solution-phase peptide synthesis. Its incorporation allows for the creation of peptides with modified structures and enhanced properties.
Chemical Biology Research
This compound is applied in chemical biology to investigate peptide structure-activity relationships and to develop peptides with specific biological functions. It aids in probing protein-protein interactions and designing novel biomolecules.
Drug Discovery
As an unnatural amino acid derivative, Fmoc-L-β3-homoproline can be incorporated into potential drug candidates to improve their pharmacokinetic profiles, stability, or target binding affinity.
Organic Synthesis
It serves as a chiral synthon in complex organic synthesis, enabling the construction of stereochemically defined molecules relevant to medicinal chemistry and materials science.
| Molecular weight | 351.40 |
|---|---|
| Empirical formula | C21H21NO4 |
| Assay | ≥98.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-L-β3-homoproline used for?
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Fmoc-L-β3-homoproline is primarily used as a building block in peptide synthesis, for chemical biology research, drug discovery, and organic synthesis.
What is the CAS number and molecular formula for Fmoc-L-β3-homoproline?
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The CAS number for Fmoc-L-β3-homoproline is 193693-60-6, and its molecular formula is C21H21NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-L-β3-homoproline with a purity of ≥98.0% (HPLC). It is typically supplied as a research or technical grade material and is not represented as USP, BP, or EP grade.
How should Fmoc-L-β3-homoproline be handled and stored?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Store at 2-8°C. The compound has a WGK Germany rating of 3.
How is this product shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, and this product is shipped and exported according to international regulations for chemical transport.
How can I request a quote or sample?
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Please contact our sales team directly via the website or by phone to request a quote or inquire about obtaining a sample for evaluation.
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