Fmoc-Lys(Alloc)-OH
Nα-Fmoc-Nε-Alloc-L-lysine (CAS: 146982-27-6), with the molecular formula C25H28N2O6, is a protected amino acid derivative. It is crucial in peptide synthesis, particularly for introducing lysine residues with orthogonal protection strategies. This compound features an Fmoc group on the alpha-amino function and an Alloc group on the epsilon-amino function, allowing for selective deprotection and further functionalization. Available with an assay of ≥95.0% (HPLC).
- IUPAC
- Nα-Fmoc-Nε-Alloc-L-lysine
Peptide Synthesis
This compound serves as a key building block in solid-phase and solution-phase peptide synthesis. The orthogonal protecting groups (Fmoc and Alloc) enable precise control over peptide chain elongation and modification.
Chemical Biology Research
It is utilised in the synthesis of modified peptides for studying biological processes, protein-protein interactions, and developing novel therapeutic agents. The ability to selectively deprotect the lysine side chain is advantageous for conjugations and labelling.
Drug Discovery and Development
Nα-Fmoc-Nε-Alloc-L-lysine is employed in the creation of peptide-based drug candidates. Its specific protection scheme facilitates the synthesis of complex peptide sequences with tailored pharmacological properties.
| Molecular weight | 452.50 |
|---|---|
| Empirical formula | C25H28N2O6 |
| Assay | ≥95.0% (HPLC) |
| Optical activity | [α]20/D −12±1°, c = 1% in DMF |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Nα-Fmoc-Nε-Alloc-L-lysine used for?
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Nα-Fmoc-Nε-Alloc-L-lysine is primarily used as a protected amino acid building block in peptide synthesis, especially for introducing lysine residues with orthogonal protection strategies in chemical biology and drug discovery.
What is the CAS number and molecular formula for Nα-Fmoc-Nε-Alloc-L-lysine?
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The CAS number is 146982-27-6, and the molecular formula is C25H28N2O6.
What grade and purity does Tech Serve Solutions supply for Nα-Fmoc-Nε-Alloc-L-lysine?
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Tech Serve Solutions supplies Nα-Fmoc-Nε-Alloc-L-lysine with a minimum purity of 95.0% as determined by HPLC. We do not represent this product as USP, BP, or EP grade.
How should Nα-Fmoc-Nε-Alloc-L-lysine be stored and handled?
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Nα-Fmoc-Nε-Alloc-L-lysine should be stored at 2-8°C. When handling, use appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or P1 (EN143) respirator filter. This compound is classified under WGK Germany 3.
How is Nα-Fmoc-Nε-Alloc-L-lysine shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Nα-Fmoc-Nε-Alloc-L-lysine. We ensure appropriate packaging and documentation for international shipments.
How can I request a quote or sample for Nα-Fmoc-Nε-Alloc-L-lysine?
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To request a quote or sample, please contact our sales department through the website or by phone, providing the product name and CAS number (146982-27-6).
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