Fmoc-D-Phe(2-CN)-OH
Fmoc-D-Phe(2-CN)-OH (CAS: 401620-74-4) is a cyanophenylalanine derivative with the molecular formula C25H20N2O4 and a molecular weight of 412.44 g/mol. This unnatural amino acid derivative is a valuable building block in peptide chemistry and chemical synthesis. Its unique structure allows for specialised modifications in biomolecules and the creation of novel peptide structures for research purposes.
- IUPAC
- Fmoc-2-cyano-D-phenylalanine
- Synonyms
- Fmoc-2-cyano-D-phenylalanine
Peptide Synthesis
Fmoc-D-Phe(2-CN)-OH is employed as a non-canonical amino acid in solid-phase peptide synthesis (SPPS) for incorporating modified phenylalanine residues into peptide chains. This enables the development of peptides with altered conformational properties or functionalities for research in medicinal chemistry and chemical biology.
Chemical Biology Research
This compound serves as a tool in chemical biology for creating peptides with unique structural or functional attributes. The cyano group offers a handle for further chemical modifications or for probing biological interactions.
Unnatural Amino Acid Libraries
It is utilised in the construction of unnatural amino acid libraries, expanding the scope of available building blocks for creating novel peptides and peptidomimetics with tailored properties.
| Molecular weight | 412.44 |
|---|---|
| Empirical formula | C25H20N2O4 |
| Assay | ≥98.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-D-Phe(2-CN)-OH used for?
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Fmoc-D-Phe(2-CN)-OH is primarily used in peptide synthesis and chemical biology research as a building block for incorporating modified phenylalanine residues into peptides. It is also used in the development of unnatural amino acid libraries.
What are the CAS number and molecular formula for Fmoc-D-Phe(2-CN)-OH?
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The CAS number is 401620-74-4 and the molecular formula is C25H20N2O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-D-Phe(2-CN)-OH with an assay of ≥98.0% (HPLC). TSS does not represent this product as USP, BP, EP, or pharmaceutical grade.
How should Fmoc-D-Phe(2-CN)-OH be handled and stored?
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Handle Fmoc-D-Phe(2-CN)-OH with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Store at 2-8°C.
Is Fmoc-D-Phe(2-CN)-OH a controlled substance?
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The provided data does not indicate that Fmoc-D-Phe(2-CN)-OH is a controlled substance.
How is Fmoc-D-Phe(2-CN)-OH packed and exported?
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Fmoc-D-Phe(2-CN)-OH is carefully packed to ensure product integrity during transit and is available for export globally by Tech Serve Solutions.
How can I request a quote or sample for Fmoc-D-Phe(2-CN)-OH?
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To request a quote or sample, please contact the Tech Serve Solutions sales team through our website or by telephone.
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