Fmoc-D-Phe(2-Cl)-OH
Fmoc-D-Phe(2-Cl)-OH (CAS: 205526-22-3) is a protected unnatural amino acid derivative with a molecular weight of 421.87 g/mol and the empirical formula C24H20ClNO4. Utilised in peptide synthesis, it serves as a valuable building block for incorporating modified phenylalanine residues into peptide chains. Its structure allows for precise incorporation and subsequent modification in complex biomolecule research and development.
- IUPAC
- Fmoc-2-chloro-D-phenylalanine
Peptide Synthesis
Fmoc-D-Phe(2-Cl)-OH is employed as a key building block in solid-phase and solution-phase peptide synthesis. It allows for the introduction of a 2-chloro-D-phenylalanine residue, enabling the creation of modified peptides with unique structural and functional properties for research purposes.
Chemical Biology Research
This unnatural amino acid derivative is valuable in chemical biology for constructing peptides or peptidomimetics with altered characteristics. The presence of the chlorine substituent can influence the conformation, stability, or biological activity of the resulting molecules.
Drug Discovery and Development
As a specialised intermediate, Fmoc-D-Phe(2-Cl)-OH can be used in the synthesis of novel peptide-based therapeutics or diagnostic agents. Its incorporation may confer specific pharmacological advantages or serve as a probe in structure-activity relationship studies.
Organic Synthesis
Beyond peptide chemistry, this compound can serve as a chiral building block in various organic synthesis strategies. Its defined stereochemistry and functional groups make it a useful precursor for creating complex organic molecules.
| Molecular weight | 421.87 |
|---|---|
| Empirical formula | C24H20ClNO4 |
| Assay | ≥96.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-D-Phe(2-Cl)-OH used for?
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Fmoc-D-Phe(2-Cl)-OH is primarily used as a building block in peptide synthesis and chemical biology research. It allows for the introduction of a modified phenylalanine residue into peptide structures, enabling the study of structure-activity relationships and the development of novel biomolecules.
What are the CAS number and formula for Fmoc-D-Phe(2-Cl)-OH?
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The CAS number for Fmoc-D-Phe(2-Cl)-OH is 205526-22-3. Its empirical formula (Hill notation) is C24H20ClNO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-D-Phe(2-Cl)-OH with a purity of ≥96.0% as determined by HPLC. This is suitable for research and chemical synthesis applications. TSS does not represent this product as USP, BP, EP, or other pharmacopoeial grades.
How should Fmoc-D-Phe(2-Cl)-OH be handled and stored?
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Handle Fmoc-D-Phe(2-Cl)-OH with appropriate personal protective equipment, including eyeshields and gloves. A respirator filter such as type N95 (US) or P1 (EN143) is recommended. Store the product at 2-8°C to maintain its integrity.
How is this product shipped?
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Fmoc-D-Phe(2-Cl)-OH is carefully packaged and exported by Tech Serve Solutions, adhering to all relevant shipping regulations for chemical compounds. Storage during transit is managed to maintain product quality.
How can I request a sample or quote for Fmoc-D-Phe(2-Cl)-OH?
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To request a sample or a quotation for Fmoc-D-Phe(2-Cl)-OH, please contact the Tech Serve Solutions sales team through our website or by direct enquiry, providing your contact details and desired quantity.
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