Fmoc-D-Nle-OH
Fmoc-D-Nle-OH (CAS: 112883-41-7), with the empirical formula C21H23NO4 and a molecular weight of 353.41 g/mol, is a vital unnatural amino acid derivative. It is primarily employed in chemical synthesis and peptide chemistry. This compound serves as a crucial building block for researchers and chemists developing novel peptides and complex organic molecules, contributing to advancements in chemical biology.
- IUPAC
- Fmoc-D-norleucine

Peptide Synthesis
Fmoc-D-Nle-OH is used as a protected building block in solid-phase and solution-phase peptide synthesis. Its incorporation allows for the creation of peptides with modified structures and potentially altered biological activities.
Chemical Synthesis
As an unnatural amino acid derivative, it is employed in the synthesis of non-natural peptides and peptidomimetics. These molecules are valuable in drug discovery and the development of novel chemical entities.
Chemical Biology Research
This compound aids in the study of protein structure and function by allowing the introduction of D-norleucine residues. Such modifications can probe conformational preferences and biological interactions.
| Molecular weight | 353.41 |
|---|---|
| Empirical formula | C21H23NO4 |
| Assay | ≥98.0% |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-D-Nle-OH used for?
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Fmoc-D-Nle-OH is used as an unnatural amino acid derivative in peptide synthesis and general chemical synthesis, particularly for creating modified peptides and peptidomimetics for research in chemical biology and drug discovery.
What is the CAS number and empirical formula for Fmoc-D-Nle-OH?
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The CAS number for Fmoc-D-Nle-OH is 112883-41-7 and its empirical formula is C21H23NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-D-Nle-OH with an assay of ≥98.0%. This is typically considered a research or technical grade and is not represented as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling precautions for Fmoc-D-Nle-OH?
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Appropriate personal protective equipment including eyeshields and gloves should be used. Respiratory protection may be necessary, with a type N95 (US) or type P1 (EN143) respirator filter recommended. The compound is classified with WGK Germany 3.
How is Fmoc-D-Nle-OH stored and shipped?
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Fmoc-D-Nle-OH should be stored at 2-8°C. Tech Serve Solutions offers global export services for this chemical, adhering to all necessary shipping regulations.
How can I request a sample or quote for Fmoc-D-Nle-OH?
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Please contact our sales team directly through our website or by phone to request a sample or a detailed quotation for Fmoc-D-Nle-OH.
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