Fmoc-D-Lys(Alloc)-OH
Fmoc-D-Lys(Alloc)-OH (CAS: 214750-75-1), with the molecular formula C25H28N2O6 and a molecular weight of 452.50, is a specialised D-lysine derivative. It is prominently used in solid-phase peptide synthesis (SPPS) and related chemical biology applications. This compound features orthogonal protection on its alpha-amino and epsilon-amino groups, enabling controlled peptide chain elongation and modification in complex syntheses.
- IUPAC
- Nα-Fmoc-Nε-Alloc-D-lysine,Nε-Alloc-Nα-Fmoc-D-lysine
- Synonyms
- Nα-Fmoc-Nε-Alloc-D-lysineNε-Alloc-Nα-Fmoc-D-lysine
Solid-Phase Peptide Synthesis (SPPS)
Fmoc-D-Lys(Alloc)-OH serves as a crucial building block in SPPS for incorporating D-lysine residues into peptide sequences. The Alloc group on the side chain offers orthogonal protection, allowing for selective deprotection and modification at specific points during synthesis.
Chemical Biology Research
This derivative is employed in chemical biology for creating modified peptides with specific functionalities or structures. Its unique protection strategy facilitates sophisticated molecular design and investigation of biological processes.
Drug Discovery and Development
In pharmaceutical research, Fmoc-D-Lys(Alloc)-OH is utilised for the synthesis of peptide-based therapeutics and drug candidates. Its incorporation can lead to peptides with enhanced stability, bioavailability, or targeted activity.
Bioconjugation Chemistry
The compound can be used in bioconjugation strategies, where the orthogonally protected lysine side chain allows for specific attachment of labels, drugs, or other molecules to peptides.
| Molecular weight | 452.50 |
|---|---|
| Empirical formula | C25H28N2O6 |
| Assay | ≥98.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-D-Lys(Alloc)-OH used for?
+
Fmoc-D-Lys(Alloc)-OH is primarily used as a protected amino acid derivative in solid-phase peptide synthesis (SPPS) and chemical biology research, enabling the controlled incorporation and modification of D-lysine residues in peptide chains.
What is the CAS number and formula for Fmoc-D-Lys(Alloc)-OH?
+
The CAS number for Fmoc-D-Lys(Alloc)-OH is 214750-75-1, and its empirical formula is C25H28N2O6.
What grade and purity does Tech Serve Solutions supply for Fmoc-D-Lys(Alloc)-OH?
+
Tech Serve Solutions supplies Fmoc-D-Lys(Alloc)-OH with an assay of ≥98.0% by HPLC. This product is intended for research and laboratory use and is not supplied as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling recommendations for Fmoc-D-Lys(Alloc)-OH?
+
Handling Fmoc-D-Lys(Alloc)-OH requires appropriate personal protective equipment, including eyeshields and gloves. In situations with potential for aerosol exposure, a type N95 (US) or type P1 (EN143) respirator filter should be used. The substance has a WGK Germany rating of 3, indicating a high hazard to water.
How is Fmoc-D-Lys(Alloc)-OH typically shipped and exported?
+
Fmoc-D-Lys(Alloc)-OH is stored at 2-8°C. Tech Serve Solutions, as a specialist global supplier and exporter, ensures appropriate packaging and documentation for the international shipment of this chemical.
How can I request a sample or quote for Fmoc-D-Lys(Alloc)-OH?
+
To request a sample or obtain a quote for Fmoc-D-Lys(Alloc)-OH, please contact the Tech Serve Solutions sales team via our website or direct enquiry channels.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis