Fmoc-D-Ile-OH

CAS 143688-83-9C21H23NO4Chemical Synthesis

Fmoc-D-Ile-OH (CAS: 143688-83-9), also known as Fmoc-D-isoleucine, is a chiral building block with the molecular formula C21H23NO4 and a molecular weight of 353.41 g/mol. It is a derivative of the non-proteinogenic amino acid D-isoleucine, protected with the Fmoc group for orthogonal deprotection strategies in peptide synthesis. This compound is essential for creating specific peptide sequences in chemical biology and synthesis research.

IUPAC: Fmoc-D-isoleucine
Synonyms: Fmoc-D-isoleucine

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Fmoc-D-Ile-OH (C21H23NO4) — chemical structure, CAS 143688-83-9; Chemistry, fine chemical supplied by Tech Serve Solutions

Amino Acid DerivativesChemical BiologyChemical SynthesisIsoleucinePeptide Chemistry

01 /Applications

Peptide Synthesis

Fmoc-D-Ile-OH serves as a key reagent in the solid-phase or solution-phase synthesis of peptides containing the non-natural D-isoleucine residue. Its Fmoc protection allows for selective deprotection under mild basic conditions, facilitating sequential amino acid coupling.

Chemical Biology Research

This D-amino acid derivative is utilised in the construction of peptides with modified structures or enhanced stability for biological studies. It enables the exploration of structure-activity relationships in peptidomimetics and related compounds.

Organic Synthesis

As a chiral synthon, Fmoc-D-Ile-OH is employed in complex organic syntheses where the stereospecific incorporation of a D-isoleucine moiety is required. It supports the development of novel molecules in medicinal chemistry.

02 /Properties

Molecular weight	353.41
Empirical formula	C21H23NO4
Assay	≥96.0% (HPLC)

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

143688-83-9

MDL number

MFCD00080291

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Fmoc-D-Ile-OH used for?

Fmoc-D-Ile-OH is primarily used as a protected amino acid building block in peptide synthesis, chemical biology research, and organic synthesis to introduce the D-isoleucine residue into peptide chains or complex molecules.

What are the CAS number and molecular formula for Fmoc-D-Ile-OH?

The CAS number for Fmoc-D-Ile-OH is 143688-83-9, and its molecular formula is C21H23NO4.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Fmoc-D-Ile-OH with an assay of ≥96.0% (HPLC). We do not represent this product as USP, BP, EP, or other pharmacopoeial grades.

What are the safety and handling precautions for Fmoc-D-Ile-OH?

Handling Fmoc-D-Ile-OH requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. The substance has a WGK Germany rating of 3, indicating it is hazardous to water.

How is Fmoc-D-Ile-OH packed, shipped, and exported?

Fmoc-D-Ile-OH is carefully packed according to industry standards for chemical stability and safety during transit. Tech Serve Solutions exports this product globally, adhering to all relevant shipping regulations.

How can I request a sample or quote for Fmoc-D-Ile-OH?

To request a sample or a quotation for Fmoc-D-Ile-OH, please contact our sales department through the TSS website or by calling our customer service line.