Fmoc-D-Met-OH
Fmoc-D-Met-OH (CAS: 112883-40-6), with the molecular formula C20H21NO4S and a molecular weight of 371.45 g/mol, is a crucial derivative of the amino acid methionine. This compound is primarily employed in solid-phase peptide synthesis (SPPS) for the introduction of the D-methionine residue into peptide chains. Its Fmoc protecting group facilitates controlled deprotection steps, making it valuable in the construction of complex peptides and peptidomimetics.
- IUPAC
- Fmoc-D-methionine
Peptide Synthesis
Utilised in solid-phase and solution-phase peptide synthesis to incorporate the non-proteinogenic D-methionine enantiomer. The Fmoc protecting group ensures regioselective coupling and facile deprotection under mild basic conditions, crucial for building peptides with defined sequences.
Medicinal Chemistry
Serves as a building block in the development of novel therapeutic agents. The incorporation of D-amino acids like D-methionine can influence peptide stability, receptor binding affinity, and pharmacokinetic properties of drug candidates.
Chemical Biology Research
Employed in the creation of modified peptides for studying biological processes. This includes the development of enzyme inhibitors, receptor ligands, and probes for investigating protein-protein interactions.
| Molecular weight | 371.45 |
|---|---|
| Empirical formula | C20H21NO4S |
| Assay | 98% |
| Storage temperature | 2-8°C |
| Melting point | 120-124 °C |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-D-Met-OH used for?
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Fmoc-D-Met-OH is used as a protected amino acid derivative in peptide synthesis, particularly for incorporating the D-methionine residue into peptide chains.
What are the CAS number and formula for Fmoc-D-Met-OH?
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The CAS number is 112883-40-6, and the empirical formula is C20H21NO4S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-D-Met-OH with an assay of 98%. This product is suitable for research purposes and is not represented as USP, BP, EP, or any other pharmacopoeial grade.
How should Fmoc-D-Met-OH be handled and stored?
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Fmoc-D-Met-OH should be handled with appropriate personal protective equipment. It is classified under WGK Germany 3 and requires storage at temperatures between 2-8°C.
Is Fmoc-D-Met-OH a controlled substance?
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The provided data does not indicate that Fmoc-D-Met-OH is a controlled substance.
How can I request a quote or sample of Fmoc-D-Met-OH?
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Please contact our sales team through the website or by phone to request a quotation or a sample of Fmoc-D-Met-OH.
How is Fmoc-D-Met-OH packed and exported?
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Fmoc-D-Met-OH is carefully packed to ensure stability during transit and is available for global export by Tech Serve Solutions.
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