Fmoc-D-Phe(2,4-Cl2)-OH
Fmoc-D-Phe(2,4-Cl2)-OH (CAS: 352351-61-2) is a fluorometoxycarbonyl-protected unnatural amino acid derivative with the molecular formula C24H19Cl2NO4. This compound is primarily utilized in chemical synthesis and peptide chemistry for the incorporation of modified phenylalanine residues. Its structure facilitates its use in the creation of complex peptides and peptidomimetics, contributing to advancements in chemical biology research and drug discovery.
- IUPAC
- Fmoc-2,4-dichloro-D-phenylalanine
- Synonyms
- Fmoc-2,4-dichloro-D-phenylalanine
Peptide Synthesis
This Fmoc-protected amino acid is crucial for solid-phase peptide synthesis (SPPS), enabling the introduction of a 2,4-dichlorinated D-phenylalanine residue. This allows for the study of structure-activity relationships and the development of novel peptide-based therapeutics.
Chemical Biology Research
As an unnatural amino acid derivative, Fmoc-D-Phe(2,4-Cl2)-OH serves as a valuable building block for creating peptides with altered properties. These modified peptides can be used to probe biological systems and understand protein function.
Drug Discovery
The incorporation of this unnatural amino acid into peptide sequences can lead to enhanced stability, altered binding affinities, or novel pharmacological profiles. This makes it a useful tool in the search for new drug candidates.
Organic Synthesis
Beyond peptide applications, this compound can be employed as a chiral building block in various organic synthesis routes requiring a specifically substituted phenylalanine moiety.
| Molecular weight | 456.32 |
|---|---|
| Empirical formula | C24H19Cl2NO4 |
| Assay | ≥98.0% (HPLC) |
| Storage temperature | 2-8°C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-D-Phe(2,4-Cl2)-OH used for?
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Fmoc-D-Phe(2,4-Cl2)-OH is used as a building block in peptide synthesis, particularly for incorporating unnatural amino acid residues into peptide chains. It is also applied in chemical biology research and drug discovery for developing peptides with modified properties and functions.
What are the CAS number and formula for Fmoc-D-Phe(2,4-Cl2)-OH?
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The CAS number for Fmoc-D-Phe(2,4-Cl2)-OH is 352351-61-2 and its molecular formula is C24H19Cl2NO4.
What grade and purity does Tech Serve Solutions supply for Fmoc-D-Phe(2,4-Cl2)-OH?
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Tech Serve Solutions supplies Fmoc-D-Phe(2,4-Cl2)-OH with a purity of ≥98.0% as determined by HPLC. We do not represent this product as USP, BP, or EP grade.
How should Fmoc-D-Phe(2,4-Cl2)-OH be handled and stored?
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Handle Fmoc-D-Phe(2,4-Cl2)-OH with appropriate personal protective equipment, including a dust mask (N95 type), eyeshields, and gloves. It is recommended to store the compound at 2-8°C. The product is classified as a Warning with hazards H315 (causes skin irritation), H319 (causes serious eye irritation), and H335 (may cause respiratory irritation).
Is Fmoc-D-Phe(2,4-Cl2)-OH a controlled substance?
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Based on the provided data, Fmoc-D-Phe(2,4-Cl2)-OH is not listed as a controlled substance.
How is Fmoc-D-Phe(2,4-Cl2)-OH packaged and exported?
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Tech Serve Solutions can facilitate the export of Fmoc-D-Phe(2,4-Cl2)-OH, adhering to all necessary regulations for chemical shipments. Packaging details are available upon request to ensure product integrity during transit.
How can I request a quote or sample for Fmoc-D-Phe(2,4-Cl2)-OH?
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To request a quote or a sample of Fmoc-D-Phe(2,4-Cl2)-OH, please contact our sales team through the website or via email, providing your specific requirements.
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