Fmoc-D-Homoser(Trt)-OH
Fmoc-D-Homoser(Trt)-OH (CAS: 257886-01-4) is a protected D-homoserine derivative with the molecular formula C38H33NO5 and a molecular weight of 583.67 g/mol. This compound serves as a valuable building block in peptide synthesis, particularly for introducing unnatural amino acids and for creating complex peptide structures. Its specialised nature makes it an important reagent in biochemical research and chemical synthesis.
- IUPAC
- Nα-Fmoc-O-trityl-D-homoserine
- Synonyms
- Nα-Fmoc-O-trityl-D-homoserine

Peptide Synthesis
Utilised as a key intermediate in solid-phase and solution-phase peptide synthesis. Its Fmoc and Trt protecting groups allow for selective deprotection and coupling during peptide chain elongation.
Chemical Biology Research
Employed in the development of novel peptides for biological studies, including protein mimetics and labelled peptides. Enables the creation of peptides with modified backbones or side chains.
Biochemical Reagent
Acts as a specialised reagent for researchers in biochemistry and medicinal chemistry. Facilitates the exploration of structure-activity relationships in peptide-based therapeutics and diagnostics.
| Molecular weight | 583.67 |
|---|---|
| Empirical formula | C38H33NO5 |
| Assay | ≥98.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-D-Homoser(Trt)-OH used for?
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Fmoc-D-Homoser(Trt)-OH is primarily used as a protected amino acid building block in peptide synthesis, enabling the incorporation of D-homoserine with specific protecting groups for further chemical modifications and research applications.
What are the CAS number and formula for Fmoc-D-Homoser(Trt)-OH?
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The CAS number is 257886-01-4 and the empirical formula is C38H33NO5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-D-Homoser(Trt)-OH with an assay of ≥98.0% (HPLC). This product is supplied for research and laboratory use and is not intended for USP, BP, EP, or other pharmacopoeia standards.
What are the safety considerations for handling Fmoc-D-Homoser(Trt)-OH?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound has a WGK Germany rating of 3, indicating a high hazard.
How is Fmoc-D-Homoser(Trt)-OH stored and shipped?
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It is recommended to store Fmoc-D-Homoser(Trt)-OH at 2-8°C. Tech Serve Solutions is a global supplier and exporter, equipped to handle the packaging and shipping requirements for fine chemicals worldwide.
How can I request a quote or sample for Fmoc-D-Homoser(Trt)-OH?
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Please contact our sales team via our website or direct contact channels to request a quote or a sample of Fmoc-D-Homoser(Trt)-OH. Our team will be pleased to assist you with your specific requirements.
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