Fmoc-D-Phe(3,4-Cl2)-OH

CAS 177966-58-44-Cl2)-OHChemical Synthesis

Fmoc-D-Phe(3,4-Cl2)-OH (CAS: 177966-58-4) is a protected unnatural amino acid derivative with the molecular formula C24H19Cl2NO4. It features a dichloro-substituted phenylalanine residue protected with the Fmoc group, making it suitable for solid-phase peptide synthesis. This compound is primarily utilised in chemical synthesis and peptide chemistry for the incorporation of modified amino acids into peptide chains, advancing chemical biology research.

IUPAC: Fmoc-3,4-dichloro-D-phenylalanine
Synonyms: Fmoc-3,4-dichloro-D-phenylalanineFmoc-D-3,4-dichlorophenylalanine

Email us

Fmoc-D-Phe(3,4-Cl2)-OH (4-Cl2)-OH) — chemical structure, CAS 177966-58-4; Chemistry, fine chemical supplied by Tech Serve Solutions

Chemical BiologyChemical SynthesisPeptide ChemistryPhenylalanine Derivatives

01 /Applications

Peptide Synthesis

Fmoc-D-Phe(3,4-Cl2)-OH is a valuable building block in Fmoc solid-phase peptide synthesis (SPPS). It allows for the precise introduction of a 3,4-dichloro-D-phenylalanine residue into peptide sequences, facilitating the study of structure-activity relationships.

Chemical Biology

The incorporation of unnatural amino acids like Fmoc-D-Phe(3,4-Cl2)-OH can confer unique properties to peptides. This enables researchers to investigate protein function, develop novel therapeutics, or create peptide-based probes for biological studies.

Chemical Synthesis

This compound serves as a versatile intermediate in organic synthesis. Its protected amino acid structure and specific substitution pattern make it useful for constructing complex molecules and peptidomimetics.

02 /Properties

Molecular weight	456.32
Empirical formula	C24H19Cl2NO4
Assay	≥96.0% (HPLC)
Storage temperature	2-8°C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

177966-58-4

MDL number

MFCD00273472

Beilstein registry

9016647

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Fmoc-D-Phe(3,4-Cl2)-OH used for?

Fmoc-D-Phe(3,4-Cl2)-OH is used as a protected unnatural amino acid derivative in Fmoc solid-phase peptide synthesis and as an intermediate in chemical synthesis and chemical biology research for creating modified peptides and complex molecules.

What is the CAS number and chemical formula for Fmoc-D-Phe(3,4-Cl2)-OH?

The CAS number is 177966-58-4, and the empirical formula is C24H19Cl2NO4.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Fmoc-D-Phe(3,4-Cl2)-OH with an assay of ≥96.0% (HPLC). It is supplied for research and laboratory use and is not represented as USP, BP, EP, or pharmaceutical grade.

How should Fmoc-D-Phe(3,4-Cl2)-OH be handled and stored?

Handle with appropriate personal protective equipment, including eyeshields and gloves. Use a type N95 (US) or type P1 (EN143) respirator filter if needed. Store at 2-8°C.

Is Fmoc-D-Phe(3,4-Cl2)-OH a controlled substance?

There is no indication in the provided data that Fmoc-D-Phe(3,4-Cl2)-OH is a controlled substance.

How is this product shipped and exported?

Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, and this product can be shipped and exported internationally according to regulations.