Fmoc-D-Phe(3-CN)-OH

CAS 205526-37-0C25H20N2O4Chemical Synthesis

Fmoc-D-Phe(3-CN)-OH (CAS: 205526-37-0) is a chemically synthesised unnatural amino acid derivative with the molecular formula C25H20N2O4 and a molecular weight of 412.44 g/mol. This compound is a valuable building block in peptide chemistry and chemical synthesis. It is supplied with a minimum purity of 98.0% (HPLC) and requires storage at 2-8°C.

IUPAC: Fmoc-3-cyano-D-phenylalanine
Synonyms: Fmoc-3-cyano-D-phenylalanine

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Fmoc-D-Phe(3-CN)-OH (C25H20N2O4) — chemical structure, CAS 205526-37-0; Chemistry, fine chemical supplied by Tech Serve Solutions

Chemical BiologyChemical SynthesisPeptide ChemistryPhenylalanine Derivatives

01 /Applications

Peptide Synthesis

Fmoc-D-Phe(3-CN)-OH serves as a modified phenylalanine residue in solid-phase peptide synthesis. Its incorporation allows for the creation of peptides with unique structural and functional properties, particularly in the field of peptide-based drug discovery.

Chemical Biology Research

As an unnatural amino acid, this compound is utilised in chemical biology to introduce specific modifications into biomolecules. This facilitates studies on protein structure-function relationships and the development of novel therapeutic agents.

Organic Synthesis Intermediate

The molecule acts as a versatile intermediate in complex organic synthesis pathways. Its functional groups, including the Fmoc protecting group and the cyano-substituted phenyl ring, enable diverse chemical transformations.

02 /Properties

Molecular weight	412.44
Empirical formula	C25H20N2O4
Assay	≥98.0% (HPLC)
Storage temperature	2-8°C
Impurities tested	~15% 2-propanol

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

205526-37-0

MDL number

MFCD00797586

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Fmoc-D-Phe(3-CN)-OH used for?

Fmoc-D-Phe(3-CN)-OH is primarily used as a building block in peptide synthesis and as an intermediate in chemical biology and organic synthesis research, allowing for the creation of modified peptides and biomolecules.

What are the CAS number and molecular formula for Fmoc-D-Phe(3-CN)-OH?

The CAS number is 205526-37-0 and the molecular formula is C25H20N2O4.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Fmoc-D-Phe(3-CN)-OH with a purity of ≥98.0% (HPLC). TSS does not represent this product as USP, BP, or EP grade.

How should Fmoc-D-Phe(3-CN)-OH be handled and stored?

Handle with appropriate personal protective equipment including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Store at 2-8°C.

Is Fmoc-D-Phe(3-CN)-OH a controlled substance?

The provided data does not indicate that Fmoc-D-Phe(3-CN)-OH is a controlled substance.

How is Fmoc-D-Phe(3-CN)-OH packaged for export?

Products are carefully packaged to ensure stability during transit and are exported globally by Tech Serve Solutions, adhering to all necessary shipping regulations.