2-Chloro-6-(trifluoromethyl)pyridine-3-carboxylic acid
2-Chloro-6-(trifluoromethyl)pyridine-3-carboxylic acid (CAS: 280566-45-2; C7H3ClF3NO2) is a halogenated pyridine derivative with a molecular weight of 225.55 g/mol. Supplied at 97% purity, this compound serves as a key building block in organic synthesis, particularly within the pharmaceutical and agrochemical sectors. Its trifluoromethyl and carboxylic acid functionalities make it a valuable intermediate for creating complex molecular structures. Tech Serve Solutions offers this chemical for research and development purposes.
- IUPAC
- 2-Chloro-6-(trifluoromethyl)nicotinic acid

Pharmaceutical Intermediate
Utilised in the synthesis of active pharmaceutical ingredients (APIs). The pyridine core and trifluoromethyl group are common features in various drug candidates.
Agrochemical Synthesis
Serves as a precursor for the development of novel herbicides, insecticides, and fungicides. Its structural motifs can impart specific biological activities.
Organic Synthesis Building Block
A versatile reagent for introducing the 2-chloro-6-(trifluoromethyl)pyridine moiety into larger molecules. Useful in creating diverse chemical libraries for screening.
Material Science Research
Potentially used in the development of functional materials where halogenated heterocyclic structures are beneficial for specific properties.
| Molecular weight | 225.55 |
|---|---|
| Empirical formula | C7H3ClF3NO2 |
| Assay | 97% |
| Melting point | 117-120 °C |

Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P305IF IN EYES
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-6-(trifluoromethyl)pyridine-3-carboxylic acid used for?
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This compound is primarily used as a building block in organic synthesis, particularly as an intermediate in the development of pharmaceuticals and agrochemicals.
What are the CAS number and chemical formula for this product?
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The CAS number is 280566-45-2 and the empirical formula (Hill notation) is C7H3ClF3NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical at a minimum purity of 97%. It is intended for research and laboratory use and is not supplied as USP, BP, EP, or any other pharmacopoeia grade.
How should 2-Chloro-6-(trifluoromethyl)pyridine-3-carboxylic acid be handled?
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This compound is classified as Danger. It is toxic if swallowed and causes skin and serious eye irritation, and may cause respiratory irritation. Handle with appropriate personal protective equipment in a well-ventilated area. Refer to the Safety Data Sheet (SDS) for comprehensive handling instructions.
Is this chemical shipped or exported internationally?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including this product, adhering to all relevant shipping and export regulations.
How can I request a sample or a quote for this chemical?
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To request a sample or a quote, please contact our sales team through the website or by phone, providing the product name and CAS number.
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