Fmoc-Asp(OBzl)-OH
Fmoc-Asp(OBzl)-OH (CAS: 86060-84-6; C26H23NO6) is a protected amino acid derivative utilised in peptide synthesis. It features the Fmoc protecting group on the alpha-amino group and a benzyl ester protecting the side-chain carboxyl group of aspartic acid. This dual protection strategy is crucial for controlled peptide chain elongation. The compound is suitable for research and development applications in chemical biology and synthesis.
- IUPAC
- Fmoc-L-aspartic acid 4-benzyl ester
Peptide Synthesis
Serves as a key building block in solid-phase and solution-phase peptide synthesis. The Fmoc group allows for facile deprotection under mild basic conditions, enabling stepwise addition of amino acids to a growing peptide chain.
Biochemical Research
Utilised in studies involving the synthesis of peptides with specific sequences for investigating protein function, enzyme activity, or developing peptide-based therapeutics.
Chemical Biology
Enables the construction of complex biomolecules and peptidomimetics for exploring biological pathways and developing novel molecular probes.
Organic Synthesis
Acts as a chiral synthon in the development of complex organic molecules where precise stereochemistry and functional group manipulation are required.
| Molecular weight | 445.46 |
|---|---|
| Empirical formula | C26H23NO6 |
| Assay | ≥98.0% (HPLC) |
| Optical activity | [α]20/D −20.0±2°, c = 1% in DMF |
| Storage temperature | 2-8°C |
| Impurities tested | ≤1% water |
| Melting point | 120-130 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Asp(OBzl)-OH used for?
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Fmoc-Asp(OBzl)-OH is primarily used as a protected amino acid building block in solid-phase and solution-phase peptide synthesis, as well as in chemical biology and organic synthesis research.
What is the CAS number and formula for Fmoc-Asp(OBzl)-OH?
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The CAS number is 86060-84-6 and the empirical formula is C26H23NO6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-Asp(OBzl)-OH with an assay of ≥98.0% (HPLC), containing ≤1% water. This is suitable for research and development purposes. TSS does not represent this product as USP, BP, or EP grade.
How should Fmoc-Asp(OBzl)-OH be handled and stored?
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Handle Fmoc-Asp(OBzl)-OH with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator filter (type N95 or P1). Store the compound at 2-8°C.
Is Fmoc-Asp(OBzl)-OH a controlled substance?
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The provided data does not indicate that Fmoc-Asp(OBzl)-OH is a controlled substance.
How is Fmoc-Asp(OBzl)-OH packed and shipped?
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Fmoc-Asp(OBzl)-OH is carefully packed to maintain its integrity during storage and transit. Tech Serve Solutions is a global supplier and exporter experienced in handling fine chemicals.
How can I request a sample or a quote for Fmoc-Asp(OBzl)-OH?
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To request a sample or a quote, please contact the Tech Serve Solutions sales team via our website or direct contact details.
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