Fmoc-Asp(OAll)-OH
Fmoc-Asp(OAll)-OH (CAS: 146982-24-3; C22H21NO6) is a protected derivative of aspartic acid, featuring the Fmoc group for N-terminal protection and an allyl ester for side-chain protection. This compound is primarily utilised in solid-phase peptide synthesis (SPPS) and other organic synthesis applications. Its specific protecting groups allow for orthogonal deprotection strategies, making it a valuable building block in the construction of complex peptides and peptidomimetics.
- IUPAC
- Fmoc-L-aspartic acid 4-allyl ester
- Synonyms
- Fmoc-L-aspartic acid 4-allyl ester
Peptide Synthesis
Fmoc-Asp(OAll)-OH is a crucial building block in Fmoc-based solid-phase peptide synthesis. The orthogonal protecting groups facilitate controlled stepwise elongation of peptide chains.
Organic Synthesis
Beyond peptide chemistry, this compound serves as a versatile synthon in general organic synthesis, enabling the introduction of protected aspartic acid residues into various molecular architectures.
Chemical Biology Research
It is employed in the synthesis of modified peptides and conjugates for research in chemical biology, allowing for the study of protein function and interactions.
| Molecular weight | 395.41 |
|---|---|
| Empirical formula | C22H21NO6 |
| Assay | ≥98.0% (HPLC) |
| Optical activity | [α]20/D −27±2°, c = 1% in DMF |
| Storage temperature | 2-8°C |
| Melting point | 111-115 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Asp(OAll)-OH used for?
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Fmoc-Asp(OAll)-OH is primarily used as a protected amino acid derivative in solid-phase peptide synthesis and other organic synthesis applications requiring the introduction of an aspartic acid residue with specific orthogonal protection.
What are the CAS number and formula for Fmoc-Asp(OAll)-OH?
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The CAS number for Fmoc-Asp(OAll)-OH is 146982-24-3, and its empirical formula is C22H21NO6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-Asp(OAll)-OH with an assay of ≥98.0% (HPLC). This is suitable for research and synthesis purposes. TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should Fmoc-Asp(OAll)-OH be handled and stored?
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Handle Fmoc-Asp(OAll)-OH with appropriate personal protective equipment, including eyeshields and gloves. It is classified under WGK Germany 3. Store the product at 2-8°C to maintain its stability and integrity.
Is Fmoc-Asp(OAll)-OH a controlled substance?
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The provided data does not indicate that Fmoc-Asp(OAll)-OH is a controlled substance.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions packs, ships, and exports fine chemicals and reagents globally, adhering to appropriate safety and regulatory standards for chemical transport.
How can I request a sample or quote for Fmoc-Asp(OAll)-OH?
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Please contact our sales team via the website or direct inquiry channels to request a sample or obtain a quotation for Fmoc-Asp(OAll)-OH.
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