Fmoc-Asn(Dod)-OH

CAS 113534-16-0C34H32N2O7Chemical Synthesis

Fmoc-Asn(Dod)-OH (CAS: 113534-16-0) is a derivative of L-asparagine, featuring an Nα-Fmoc and an Nγ-(4,4′-dimethoxybenzhydryl) protecting group. This protected amino acid derivative has a molecular weight of 580.63 g/mol and the empirical formula C34H32N2O7. It is primarily utilised in solid-phase peptide synthesis and other chemical synthesis applications within research and development settings.

IUPAC: Nα-Fmoc-Nγ-(4,4′-dimethoxybenzhydryl)-L-asparagine
Synonyms: Nα-Fmoc-Nγ-(4,4′-dimethoxybenzhydryl)-L-asparagine

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Fmoc-Asn(Dod)-OH (C34H32N2O7) — chemical structure, CAS 113534-16-0; Chemistry, fine chemical supplied by Tech Serve Solutions

Amino Acid DerivativesAsparagineChemical BiologyChemical SynthesisPeptide Chemistry

01 /Applications

Peptide Synthesis

Fmoc-Asn(Dod)-OH is a crucial building block in solid-phase peptide synthesis (SPPS) for incorporating protected asparagine residues into peptide chains. The Nα-Fmoc group facilitates deprotection under mild basic conditions, while the Nγ-Dod group protects the side-chain amide during coupling.

Chemical Biology

This compound serves as a reagent in chemical biology for the synthesis of modified peptides or peptidomimetics. Its protected nature allows for controlled incorporation into complex biomolecular structures for studying protein-protein interactions or developing biochemical probes.

Organic Synthesis

As a functionalised amino acid derivative, Fmoc-Asn(Dod)-OH finds application in broader organic synthesis strategies. It can be employed in the construction of novel molecular architectures where a protected asparagine moiety is required.

02 /Properties

Molecular weight	580.63
Empirical formula	C34H32N2O7
Assay	≥96.0% (HPLC)
Storage temperature	2-8°C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

113534-16-0

MDL number

MFCD00065623

Beilstein registry

5204238

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Fmoc-Asn(Dod)-OH used for?

Fmoc-Asn(Dod)-OH is primarily used as a protected amino acid derivative in solid-phase peptide synthesis (SPPS) and other chemical synthesis applications within research and development.

What are the CAS number and formula for Fmoc-Asn(Dod)-OH?

The CAS number for Fmoc-Asn(Dod)-OH is 113534-16-0, and its empirical formula is C34H32N2O7.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Fmoc-Asn(Dod)-OH with a purity of ≥96.0% (HPLC). TSS does not represent this product as USP/BP/EP or any pharmacopoeia grade.

What are the safety and handling recommendations for Fmoc-Asn(Dod)-OH?

According to GHS classification, appropriate personal protective equipment includes eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound is classified with WGK Germany 3, indicating a high hazard.

How is Fmoc-Asn(Dod)-OH shipped and exported?

Fmoc-Asn(Dod)-OH is typically stored at 2-8°C. Tech Serve Solutions, a global supplier and exporter, can arrange for the shipment and export of this chemical according to international regulations.