Fmoc-Arg(Pbf)-OPfp
N-α-Fmoc-NG-2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine pentafluorophenyl ester (CAS 200132-16-7) is a protected amino acid derivative with the molecular formula C40H39N4F5O7S and a molecular weight of 814.82. This compound is primarily utilised in solid-phase peptide synthesis and other chemical synthesis applications where controlled introduction of the protected arginine residue is required. It is supplied by Tech Serve Solutions for research and development purposes.
- IUPAC
- N-α-Fmoc-NG-2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine pentafluorophenyl ester

Peptide Synthesis
Fmoc-Arg(Pbf)-OPfp serves as a crucial building block in solid-phase peptide synthesis (SPPS) using Fmoc chemistry. The Pbf protecting group on the arginine side chain is stable under Fmoc deprotection conditions and readily removed with acid cleavage cocktails.
Chemical Synthesis
This derivative is employed in general organic synthesis and medicinal chemistry for the incorporation of modified or protected arginine residues into complex molecules. Its pentafluorophenyl ester moiety facilitates efficient coupling reactions.
Research and Development
Utilised in academic and industrial research laboratories for the exploration of novel peptides, peptidomimetics, and other biologically relevant compounds. It aids in structure-activity relationship studies and the development of new therapeutic agents.
| Molecular weight | 814.82 |
|---|---|
| Empirical formula | C40H39N4F5O7S |
| Assay | ≥80% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Arg(Pbf)-OPfp used for?
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Fmoc-Arg(Pbf)-OPfp is primarily used as a protected amino acid building block in solid-phase peptide synthesis and general chemical synthesis for the introduction of arginine residues.
What is the CAS number and molecular formula?
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The CAS number for Fmoc-Arg(Pbf)-OPfp is 200132-16-7, and its molecular formula is C40H39N4F5O7S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-Arg(Pbf)-OPfp with an assay of ≥80% by HPLC. This product is intended for research and development purposes and is not supplied as USP, BP, EP, or pharmacopoeia grade.
How should Fmoc-Arg(Pbf)-OPfp be handled and stored?
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Handle Fmoc-Arg(Pbf)-OPfp with appropriate personal protective equipment, including eyeshields and gloves. A type N95 respirator filter is recommended. Store the product at 2-8°C to maintain its stability.
Is this chemical a controlled substance?
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The provided data does not indicate that Fmoc-Arg(Pbf)-OPfp is a controlled substance.
How can I request a sample or quote?
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To request a sample or a quote for Fmoc-Arg(Pbf)-OPfp, please contact the Tech Serve Solutions sales team through our website or designated contact channels.
How is this product packed, shipped, and exported?
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Fmoc-Arg(Pbf)-OPfp is carefully packed to ensure integrity during transit and is available for domestic and international export by Tech Serve Solutions.
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