Fmoc-Arg(NO2)-OH

CAS 58111-94-7C21H23N5O6Chemical Synthesis

Fmoc-Arg(NO2)-OH (CAS: 58111-94-7) is a chemically synthesised derivative of the amino acid L-arginine, featuring Nα-Fmoc and Nω-nitro protection. Its empirical formula is C21H23N5O6, with a molecular weight of 441.44 g/mol. This compound is a crucial building block in solid-phase peptide synthesis, particularly for incorporating nitroarginine residues into peptide sequences for research applications in chemical biology and peptide chemistry.

IUPAC: Nα-Fmoc-Nω-nitro-L-arginine
Synonyms: Nα-Fmoc-Nω-nitro-L-arginine

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Fmoc-Arg(NO2)-OH (C21H23N5O6) — chemical structure, CAS 58111-94-7; Chemistry, fine chemical supplied by Tech Serve Solutions

Amino Acid DerivativesArginineChemical BiologyChemical SynthesisPeptide Chemistry

01 /Applications

Peptide Synthesis

Fmoc-Arg(NO2)-OH is employed in solid-phase peptide synthesis (SPPS) to introduce Nω-nitro-L-arginine residues. This enables the construction of peptides with modified arginine side chains for research purposes.

Chemical Biology Research

The compound serves as a reagent in studies exploring the biological roles and chemical properties of modified amino acids and peptides. Its incorporation can modulate peptide structure and function.

Organic Synthesis

As a protected amino acid derivative, it is utilised in complex organic synthesis pathways requiring precise control over reactive functional groups during multi-step preparations.

02 /Properties

Molecular weight	441.44
Empirical formula	C21H23N5O6
Assay	≥98.0% (HPLC)
Storage temperature	2-8°C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

58111-94-7

MDL number

MFCD00065617

Beilstein registry

7060334

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Fmoc-Arg(NO2)-OH used for?

Fmoc-Arg(NO2)-OH is primarily used as a protected amino acid derivative in solid-phase peptide synthesis to incorporate Nω-nitro-L-arginine residues into peptides for chemical biology and research applications.

What are the CAS number and formula for Fmoc-Arg(NO2)-OH?

The CAS number for Fmoc-Arg(NO2)-OH is 58111-94-7, and its empirical formula is C21H23N5O6.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Fmoc-Arg(NO2)-OH with a purity of ≥98.0% by HPLC. This compound is suitable for research purposes and is not supplied as USP, BP, or EP grade.

How should Fmoc-Arg(NO2)-OH be handled and stored?

Handle Fmoc-Arg(NO2)-OH with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Store the product at 2-8°C.

Is Fmoc-Arg(NO2)-OH a controlled substance?

The provided data does not indicate that Fmoc-Arg(NO2)-OH is a controlled substance.

How can I request a quote or sample?

To request a quote or a sample of Fmoc-Arg(NO2)-OH, please contact the Tech Serve Solutions sales department through our website or by telephone.

How is this chemical exported?

Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Fmoc-Arg(NO2)-OH, adhering to international shipping regulations.