Fmoc-Arg(Mts)-OH
Fmoc-Arg(Mts)-OH (CAS: 88743-97-9), also known as Nα-Fmoc-Nω-(mesitylene-2-sulfonyl)-L-arginine, is a protected amino acid derivative with the molecular formula C30H34N4O6S and a molecular weight of 578.68 g/mol. It is primarily utilised in solid-phase peptide synthesis and other chemical synthesis applications. Its Nω-mesitylene-2-sulfonyl (Mts) protection offers stability under Fmoc cleavage conditions, making it a valuable building block in complex peptide chain construction.
- IUPAC
- Nα-Fmoc-Nω-(mesitylene-2-sulfonyl)-L-arginine
- Synonyms
- Nα-Fmoc-Nω-(mesitylene-2-sulfonyl)-L-arginine
Peptide Synthesis
Fmoc-Arg(Mts)-OH is a critical reagent in the Fmoc/tBu solid-phase peptide synthesis strategy. The Mts group effectively protects the guanidino functionality of arginine during coupling and deprotection steps, ensuring controlled peptide chain elongation.
Chemical Synthesis
Beyond peptide synthesis, this compound serves as a versatile building block in various organic synthesis pathways. Its specific protecting group strategy allows for selective manipulation of molecular structures in complex organic chemistry.
Research and Development
Researchers utilise Fmoc-Arg(Mts)-OH in laboratories for developing novel peptides and peptidomimetics with potential therapeutic or diagnostic applications. Its reliable performance aids in advancing biochemical and medicinal chemistry.
| Molecular weight | 578.68 |
|---|---|
| Empirical formula | C30H34N4O6S |
| Assay | ≥96.0% (HPLC) |
| Optical activity | [α]20/D −2.5±1°, c = 1.4% in methylene chloride |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Arg(Mts)-OH primarily used for?
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Fmoc-Arg(Mts)-OH is primarily used in solid-phase peptide synthesis (SPPS) as a protected building block for incorporating arginine residues into peptide chains, particularly within the Fmoc/tBu strategy.
What is the CAS number and formula for Fmoc-Arg(Mts)-OH?
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The CAS number for Fmoc-Arg(Mts)-OH is 88743-97-9, and its empirical formula is C30H34N4O6S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-Arg(Mts)-OH with an assay of ≥96.0% by HPLC. This product is suitable for research and technical applications; TSS does not represent it as USP, BP, or EP grade.
How should Fmoc-Arg(Mts)-OH be handled and stored?
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Handle Fmoc-Arg(Mts)-OH with appropriate personal protective equipment, including eyeshields and gloves. Store the chemical at 2-8°C to maintain its integrity. Refer to the safety data sheet for detailed handling information.
Is Fmoc-Arg(Mts)-OH a controlled substance?
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The provided data does not indicate that Fmoc-Arg(Mts)-OH is a controlled substance.
How can I request a sample or quote for Fmoc-Arg(Mts)-OH?
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To request a sample or obtain a quote for Fmoc-Arg(Mts)-OH, please contact our sales department through the website or by phone, providing your specific requirements and shipping details.
How is Fmoc-Arg(Mts)-OH packaged and exported?
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Fmoc-Arg(Mts)-OH is carefully packaged to ensure stability during transit and is available for global export by Tech Serve Solutions.
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