Fmoc-Ala-OH
Fmoc-Ala-OH (CAS 35661-39-3), with the molecular formula C18H17NO4 and a molecular weight of 311.33 g/mol, is a crucial protected amino acid derivative. It is widely employed in solid-phase peptide synthesis (SPPS) due to the base-labile nature of the Fmoc protecting group, which facilitates controlled deprotection during peptide chain elongation. This compound is essential for the construction of custom peptides and peptide-based therapeutics.
- IUPAC
- N-(9-Fluorenylmethoxycarbonyl)-L-alanine,Fmoc-L-alanine
- Synonyms
- N-(9-Fluorenylmethoxycarbonyl)-L-alanineFmoc-L-alanine
Peptide Synthesis
Fmoc-Ala-OH is a fundamental building block in solid-phase peptide synthesis (SPPS). The Fmoc group allows for selective deprotection under mild basic conditions, enabling sequential addition of amino acids to form peptide chains.
Research and Development
This compound is utilised in academic and industrial research laboratories for the development of novel peptide-based drugs, diagnostics, and biomaterials. Its role in combinatorial chemistry facilitates the creation of peptide libraries.
Biochemical Studies
Fmoc-L-alanine is used in studies involving enzyme substrates, protein mimetics, and other biochemical investigations where precisely synthesised peptide sequences are required.
| Molecular weight | 311.33 |
|---|---|
| Empirical formula | C18H17NO4 |
| Assay | 95% |
| Grade | purum |
| Optical activity | [α]20/D −18°, c = 1 in DMF |
| Storage temperature | 2-8°C |
| Melting point | 147-153 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Ala-OH used for?
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Fmoc-Ala-OH is primarily used as a protected amino acid building block in solid-phase peptide synthesis (SPPS) for the construction of peptide chains and in various chemical and biochemical research applications.
What is the CAS number and formula for Fmoc-Ala-OH?
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The CAS number for Fmoc-Ala-OH is 35661-39-3, and its molecular formula is C18H17NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-Ala-OH with a purity of 95% (purum grade). We do not represent this product as USP, BP, or EP grade.
How should Fmoc-Ala-OH be handled and stored?
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Fmoc-Ala-OH should be handled with appropriate personal protective equipment, including eyeshields and gloves. It requires storage at 2-8°C to maintain its stability and integrity.
Is Fmoc-Ala-OH a controlled substance?
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The provided data does not indicate that Fmoc-Ala-OH (CAS 35661-39-3) is a controlled substance.
How are your chemicals exported and shipped?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents. We adhere to strict international shipping regulations for chemical exports.
How can I request a sample or quote for Fmoc-Ala-OH?
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To request a sample or quote for Fmoc-Ala-OH, please contact our sales team through the website or provide your details via the inquiry form. Specify the required quantity and delivery location.
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