Fmoc-6-Ahx-OH
Fmoc-6-Ahx-OH (CAS: 88574-06-5; Formula: C21H23NO4) is a derivative of hexanoic acid used in chemical synthesis and peptide chemistry. With a molecular weight of 353.41 g/mol, it serves as a valuable building block in the creation of peptides and other complex organic molecules. Its application spans research in chemical biology and the development of unnatural amino acid derivatives, contributing to advancements in these fields.
- IUPAC
- 6-(Fmoc-amino)caproic acid,6-(Fmoc-amino)hexanoic acid
- Synonyms
- 6-(Fmoc-amino)caproic acid6-(Fmoc-amino)hexanoic acid

Peptide Synthesis
Fmoc-6-Ahx-OH is utilized as a key intermediate in solid-phase peptide synthesis (SPPS). Its Fmoc protecting group allows for controlled chain elongation, while the hexanoic acid linker provides a flexible spacer in the peptide sequence.
Chemical Biology Research
This compound is employed in chemical biology for the synthesis of modified peptides or peptidomimetics. It can be incorporated into biomolecules to study protein-protein interactions or to develop novel probes for biological systems.
Unnatural Amino Acid Development
As an unnatural amino acid derivative, Fmoc-6-Ahx-OH enables the creation of peptides with altered properties. This is critical for designing peptides with enhanced stability, specific binding affinities, or unique functionalities.
Organic Synthesis
Beyond peptide chemistry, Fmoc-6-Ahx-OH serves as a versatile building block in general organic synthesis. Its functional groups can be manipulated to construct diverse molecular architectures for various research purposes.
| Molecular weight | 353.41 |
|---|---|
| Empirical formula | C21H23NO4 |
| Assay | ≥97.0% (HPLC) |
| Storage temperature | 2-8°C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-6-Ahx-OH used for?
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Fmoc-6-Ahx-OH is primarily used in peptide synthesis, chemical biology research, and the development of unnatural amino acid derivatives. It acts as a protected amino acid building block for creating modified peptides and other complex organic molecules.
What are the CAS number and formula for Fmoc-6-Ahx-OH?
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The CAS number for Fmoc-6-Ahx-OH is 88574-06-5, and its empirical formula is C21H23NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-6-Ahx-OH with a purity of ≥97.0% as determined by HPLC. This product is intended for research and laboratory use, and TSS does not represent it as USP, BP, EP, or any other pharmacopoeia grade.
How should Fmoc-6-Ahx-OH be handled and stored?
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Fmoc-6-Ahx-OH is classified as a Warning substance, causing skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask (type N95 or equivalent), eyeshields, and gloves. Store at 2-8°C to maintain stability.
Is Fmoc-6-Ahx-OH a controlled substance?
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The provided data does not indicate that Fmoc-6-Ahx-OH is a controlled substance.
How is Fmoc-6-Ahx-OH packed and exported?
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Fmoc-6-Ahx-OH is carefully packed to ensure safe transit and is available for global export by Tech Serve Solutions.
How can I request a quote or sample of Fmoc-6-Ahx-OH?
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To request a quote or sample of Fmoc-6-Ahx-OH, please contact our sales team through the website or by phone.
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