Fmoc-5-Ava-OH
Fmoc-5-Ava-OH (CAS: 123622-48-0), with the empirical formula C20H21NO4 and a molecular weight of 339.39 g/mol, is a crucial building block in peptide synthesis. As a derivative of the unnatural amino acid 5-aminovaleric acid, it offers extended chain lengths for peptide constructs. This compound is primarily utilised in chemical biology and synthesis laboratories for the construction of complex peptides and peptidomimetics, enabling research into novel biomaterials and therapeutic agents.
- IUPAC
- 5-(Fmoc-amino)pentanoic acid,5-(Fmoc-amino)valeric acid
- Synonyms
- 5-(Fmoc-amino)pentanoic acid5-(Fmoc-amino)valeric acid

Peptide Synthesis
Fmoc-5-Ava-OH serves as a protected unnatural amino acid in solid-phase peptide synthesis (SPPS) and solution-phase methods. Its incorporation allows for the introduction of a flexible linker or modified side chain into peptide sequences, facilitating the development of novel therapeutics and research tools.
Chemical Biology Research
This compound is valuable for constructing peptides with altered structural or functional properties. Researchers use Fmoc-5-Ava-OH to create peptide conjugates, probes, and modified proteins for studying biological processes and developing diagnostic assays.
Custom Synthesis
As a key intermediate, Fmoc-5-Ava-OH is employed in custom synthesis projects for academic and industrial clients. Its unique structure enables the creation of bespoke peptides with specific modifications for diverse research applications.
| Molecular weight | 339.39 |
|---|---|
| Empirical formula | C20H21NO4 |
| Assay | ≥98.0% (HPLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-5-Ava-OH used for?
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Fmoc-5-Ava-OH is primarily used in peptide synthesis and chemical biology research as a protected unnatural amino acid to introduce a 5-aminovaleric acid residue into peptide chains, enabling the creation of modified peptides with unique structural or functional properties.
What are the CAS number and molecular formula for Fmoc-5-Ava-OH?
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The CAS number for Fmoc-5-Ava-OH is 123622-48-0, and its empirical formula is C20H21NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-5-Ava-OH with an assay of ≥98.0% by HPLC. This product is supplied for research and development purposes and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should Fmoc-5-Ava-OH be handled and stored?
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Handling Fmoc-5-Ava-OH requires appropriate personal protective equipment, including eyeshields and gloves. A respirator filter of type N95 (US) or P1 (EN143) is recommended. It should be stored at 2-8°C to maintain stability.
Is Fmoc-5-Ava-OH a controlled substance?
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The provided data does not indicate that Fmoc-5-Ava-OH is a controlled substance.
How is Fmoc-5-Ava-OH packed and exported?
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Tech Serve Solutions, as a specialist global supplier and exporter, ensures appropriate packaging for chemicals like Fmoc-5-Ava-OH for domestic and international shipment. Specific packaging details for export will be provided upon request.
How can I request a sample or quote for Fmoc-5-Ava-OH?
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To request a sample or a quotation for Fmoc-5-Ava-OH, please contact our sales team through the enquiry form on our website or by calling our office directly.
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